Preview

Juvenile Huntington's Disease

Good Essays
Open Document
Open Document
764 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Juvenile Huntington's Disease
Huntington's disease

Anna Richards 4th period 12/7/16

Page Break

In 1872, the American physician George Huntington wrote about an illness that he called "an heirloom from generations away back in the dim past." One of its earliest names was chorea. Until recently, scientists understood very little about HD and could only watch as the disease continued to pass from generation to generation. Families saw the disease destroy their loved ones' ability to feel, think, and move. Scientist working disorders and stoke have recently got a break through with what's going on.

It is caused by getting passed down from parents. HD results from genetically programmed degeneration of nerve cells, called neurons, in certain
…show more content…
This is called Juvenile Huntington's disease. A noticeable side affect of having HD at a young age is how your rapid decline in school performance. Simple things like changes in handwriting and slight problems with movement, such as slowness, rigidity, tremor, and rapid muscular twitching, called myoclonus. One third of them have recurrent seizures. Both juvenile and adult-onset have effect of dementia.

What are the differences with juvenile and adult-onset? Both of them forms of the disease result in neurological damage that causes sever movement disorders. "But the difference is adult-onset HD is normally characterized by dance-like chorea, while juvenile HD more often results in rigidity and stiffness of muscles." Link HD Kids will most likely have the symptoms Loss of previously learned academic, physical skills, Behavioral problems, Contracted and rigid muscles that affect gait (especially in young children), bad handwriting, tremors, slight involuntary movements, or Seizures. Juvenile HD do not experience the chorea. Chorea is more likely to be present in individuals who have an age of onset from 15-18 years. Usually around age 15 they would have more adult symptoms. Juvenile onset usually results in death within 10 years. For adults usually 10-30

You May Also Find These Documents Helpful

  • Good Essays

    According to American Journal of Neuroradiology (2002), leukodystrophy is a progressive disease of myelin sheath in which a genetically determined metabolic defect results in confluent destruction, or failed development, of central white matter. Most leukodystrophies are autosomal recessive or X-linked recessive with onset in early childhood. Dominantly inherited leukodystrophies with onset in adulthood are rare (http://www.ajnr.org/content/27/4/904.full#xref-ref-1-1).…

    • 708 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Huntington’s disease is a genetic disorder that can not be incurable that is inherited in an autosomal dominant manner.…

    • 125 Words
    • 1 Page
    Good Essays
  • Powerful Essays

    In the world we live in, we are vulnerable to any number of neurological disorders. One such disease is Huntington’s Chorea. Progressive and degenerative, Huntington’s causes the one’s nerve cells in the brain to waste away. This causes personality changes such as depression and anger, decrease of cognitive abilities such as learning new information, involuntary facial movements and seizures in the early stages. Later symptoms include chorea which is involuntary movements like sudden jerks throughout the body, slurred speech, dementia and many more. (Mayo clinic, n.d) ref to one world factors…

    • 1541 Words
    • 7 Pages
    Powerful Essays
  • Good Essays

    Tay Sachs Disease Essay

    • 853 Words
    • 4 Pages

    It is caused by the presence of the homozygous recessive gene on chromosome 15 that codes for the production of hexosaminidase-A (Hex-A). Since the body has no HexA, a fatty substance is allowed build up abnormally in nerve cells, which eventually damages the cells and the brain. When a child is two years old, they will suffer seizures and degrading mental function. Their mental abilities continue to worsen to a point of paralyses and blindness, and death comes around age five.…

    • 853 Words
    • 4 Pages
    Good Essays
  • Better Essays

    Many diseases and disorders that affect the population have an early onset that begins when generations are young. Duchenne Muscular Dystrophy, DMD, is no different with a typical onset of symptoms between the ages three and five. DMD is characterized by muscle weakness that worsens rapidly. When a child, who has been diagnosed with DMD the condition can spread to the cardiovascular and respiratory muscles by the time they mature into teenagers. The beginning of the condition affects the shoulders, upper arm, hip and leg muscles.…

    • 1398 Words
    • 6 Pages
    Better Essays
  • Good Essays

    Huntington’s disease is an autosomal dominant neurodegenerative disorder characterized by an abnormally high number of CAG repeats (polyglutamine) in the huntingtin (HTT) gene (also known as IT15), found in the short arm of chromosome 4, specifically, p16.3 (Buetow et al. 1991). Symptoms of this disorder include chorea (involuntary jerking movements), cognitive deficits, motor deficits, and changes in behavior. This disease gets progressively worse over time, starting with subtle behavioral, cognitive, and physical changes, progressing to severe memory decline, substantial personality changes, and debilitating motor and physiological deficits, and ending in death due to the incapacitating symptoms (Zuccato et al. 2010). Patients are generally…

    • 1196 Words
    • 5 Pages
    Good Essays
  • Satisfactory Essays

    How does this disorder affect the body? Be specific – which parts of the body does it affect, and how.…

    • 347 Words
    • 2 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Muscular Dystrophy Essay

    • 446 Words
    • 2 Pages

    Myotonic MD is the most common form among adults, while Duchenne MD is the most common form among children (it affects only boys). Some are severe diseases at birth that lead to early death. Others follow very slow progressive courses over many decades and may be compatible with a normal lifespan.…

    • 446 Words
    • 2 Pages
    Satisfactory Essays
  • Better Essays

    As it has been said previously, Huntington’s disease is hereditary (Team C, 2011). That being said, if you inherit a copy of the gene for the disease from either parent, you will develop it at some point in your life (Team C, 2011). If you have one parent that…

    • 1220 Words
    • 5 Pages
    Better Essays
  • Good Essays

    Symptoms in children may be different than adults. (These results can consist of appearing dazed and being tired easily. Other mood problems consist of being cranky and irritable. Children may also have trouble walking and have a loss of balance. Crying excessively and change of eating patterns are signs as well.)…

    • 694 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Describe the expected pattern of children and young people's development from birth to 19 years,to include;…

    • 1968 Words
    • 8 Pages
    Satisfactory Essays
  • Better Essays

    Huntington’s Disease, previously known as Huntington’s chorea, is a long term brain disorder that eventually leads to uncontrolled movement, problems with emotions, loss of cognitive abilities such as memorization, increased involuntary movements, behavioral symptoms, and degeneration of nerve cells in the brain(1). This disease has been recognized as a disorder for hundreds of years, but however, only recently a cause was instituted to explain the effects. During the eighteenth and nineteenth centuries, gene heredity was poorly understood as people who had the gene coding for the disease, died before many symptoms could appear. Huntington's Disease was first identified as an…

    • 973 Words
    • 4 Pages
    Better Essays
  • Good Essays

    The striatum in the brain is believed to play a large factor in the cause of the symptoms of Huntington’s disease. Its function is to process all of the signals within the neocortex and then pass them to other parts of the basal ganglia and frontal lobes. The parts of the brain that the striatum sends its information to are known for playing a large role in the planning and execution of a person’s bodily movement. Huntington’s disease seems to disrupt the striatum’s pathway in sending its messages, which then interferes with the parts of the brain that control movement. This pathway disruption is what causes the loss of muscle control for those who suffer from the disease. As a person is first affected, the chorea starts off as minor but as the disease progresses more damage is done to the brain, which results in an increase in the severity of symptoms. This is believed to be the reason behind eighty percent of brains belonging to those who have died of Huntington’s disease having significant atrophy to their frontal lobes. Along with a loss of frontal lobe tissue, this disease also causes a loss of striatal tissue, a noticeable amount of one hundred percent of all Huntington’s disease brains examined. Expectedly, on average a brain that has gone through the symptoms of Huntington’s disease is on average smaller than a normal unaffected…

    • 1026 Words
    • 5 Pages
    Good Essays
  • Good Essays

    Parkinson Disease

    • 355 Words
    • 2 Pages

    Parkinson disease is a disease of the nervous system that affects movement. The disease is characterized by progressive loss of nigrostriatal dopaminergic cells due to a dopamine deficiency. Brain cell connections degenerate and die causing memory loss and destroying other important mental functions. Researchers are still unsure as to why the disease develops. A combination of genetic and environmental factors are thought to contribute to the risk of getting Parkinson's, says Catherine Kopil, PhD.Several genetic mutations have been found that are linked to Parkinson's disease, and lifestyle may also play a role.…

    • 355 Words
    • 2 Pages
    Good Essays
  • Good Essays

    The effects of DCD can range from mild to severe. There, but early degree of the effects vary depending on the environmental tasks and the demands placed on the child. The difficulties are experienced in a variety of areas or specific activities. There is no cure, but early intervention and treatment will help to reduce and emotional, physical and social consequences.…

    • 3499 Words
    • 14 Pages
    Good Essays

Related Topics