Importance of Colloidal Dispersion in Pharmacy
Importance of colloidal dispersion in pharmacy Pharmaceutical Applications of colloids:
Colloids are extensively used for modifying the properties of pharmaceutical agents. The most common property that is affected is the solubility of a drug .However, colloidal forms of many drugs exhibits substantially different properties when compared with traditional forms of these drugs. Certain medicinals have been found to possess unusual or increased therapeutic properties when formulated in the colloidal state. Another important pharmaceutical application of colloid is their use as drug delivery system. The most often used colloid type drug delivery systems include hydrogels, microspheres, microemulsions, liposomes, micelles, nanoparticles and nanocrystals. Here we mention the main characteristics of each colloidal delivery system.
Hydrogels:
Hydrogel is a colloidal gel in which water is the dispersion medium. It (also called aquagel) is a network of polymer chains that are hydrophilic, sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are highly absorbent (they can contain over 99% water) natural or synthetic polymers. Hydrogels also possess a degree of flexibility very similar to natural tissue, due to their significant water content. These hydrogels have the ability to sense changes of pH, temperature, or the concentration of metabolite and release their load as result of such a change Natural and synthetic hydrogels are used for wound healing, as scaffolds in tissue engineering, and as sustained- release delivery systems. When used as scaffolds for tissue engineering, hydrogels may contain human cells to stimulate tissue repair, since they are loaded with pharmaceutical ingredients, hydrogels provide a sustained drug release. Light-sensitive, pressure- responsive, and electro-sensitive hydrogels also have the potential to be used in drug delivery. Environmentally sensitive hydrogels include slow response time, limited
Colloids are extensively used for modifying the properties of pharmaceutical agents. The most common property that is affected is the solubility of a drug .However, colloidal forms of many drugs exhibits substantially different properties when compared with traditional forms of these drugs. Certain medicinals have been found to possess unusual or increased therapeutic properties when formulated in the colloidal state. Another important pharmaceutical application of colloid is their use as drug delivery system. The most often used colloid type drug delivery systems include hydrogels, microspheres, microemulsions, liposomes, micelles, nanoparticles and nanocrystals. Here we mention the main characteristics of each colloidal delivery system.
Hydrogels:
Hydrogel is a colloidal gel in which water is the dispersion medium. It (also called aquagel) is a network of polymer chains that are hydrophilic, sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are highly absorbent (they can contain over 99% water) natural or synthetic polymers. Hydrogels also possess a degree of flexibility very similar to natural tissue, due to their significant water content. These hydrogels have the ability to sense changes of pH, temperature, or the concentration of metabolite and release their load as result of such a change Natural and synthetic hydrogels are used for wound healing, as scaffolds in tissue engineering, and as sustained- release delivery systems. When used as scaffolds for tissue engineering, hydrogels may contain human cells to stimulate tissue repair, since they are loaded with pharmaceutical ingredients, hydrogels provide a sustained drug release. Light-sensitive, pressure- responsive, and electro-sensitive hydrogels also have the potential to be used in drug delivery. Environmentally sensitive hydrogels include slow response time, limited