Complement system is an important factor that ‘complements’ the immune system. Do you agree with this statement? Explain.
I agreed with that statement. By the name, we know already the function of complement system. It is to ‘complement’ the antibacterial activity of antibody. To be more specific, complement system is plasma proteins that is made up in a large number that can react with one another to opsonize all the pathogens and induce a series of inflammatory responses that can helps to fight the infections. Complement system consists of 20 different serum proteins that are produced by variety of cells such as liver cells, macrophages and gut epithelial cells. The overall function of complement system is to control on the inflammatory.
There is a way to activate the complement system. The complement activation can be done by a reaction where one component acts enzymatically on the next component to generate an enzyme that can be mediated to the next step.
The activation of complement system can helps the immune system by opsonisation of microorganisms, recruitment and activation of phagocytes to the sites of infection. It also participated in regulation of antibody responses and aid in clearance of immune complexes and damaged cells.
There are three biochemical pathways that can be activated on pathogens surfaces by the complement system. Those are, classical complement pathway, alternative complement pathway and lectin pathway. By this complement activation system, it really helps the immune system in the body and very important.