Thesis Statement: To inform the audience about Hemophilia B or Factor IX deficiency. I. Introduction
A. Most everyone can recall getting a cut or bumping into something right? Some of you may have even thought when looking at the cut it would never stop bleeding or wondering when the bruise would go away. Well, in some peoples’ lives the thought of when the injury will stop bleeding or when the bruise will go away is a daily reality. B. Today I am going to talk about what Hemophilia B or Factor IX deficiency is, provide some history of how it was discovered, explain some signs and symptoms of the disease, explain how it is treated, and explain how my son lives with it. II. Body
[Transition: Let’s start by telling you what it is and how it was discovered.] A. Hemophilia is a type of bleeding disorder that causes the blood to take a long time to clot. 1. This can cause abnormal bleeding, or bleeding that won’t stop. 2. People with hemophilia have too little or even no blood clotting proteins, called factor. 3. Hemophilia mostly affects males, and is primarily inherited or passed down through families. 4. Females are the primary carriers of the gene.
B. Originally thought to be a single disease.
5. In the 1950’s, doctors discovered two forms of the disease. a. Hemophilia A or factor VIII deficiency is the most common form of hemophilia and occurs in about 1 in every 10,000 males. A 2008 global survey by The World Federation of Hemophilia reported that there were about 12,000 people with hemophilia in the US and 108,000 worldwide. b. Hemophilia B or factor IX deficiency is the second most common form of hemophilia and occurs in about 1 in 20,000 – 50,000 people. The 2008 global survey by The World Federation of Hemophilia reported that there were about 4,000 people with hemophilia B in the US and 22,000 worldwide. 6. The Christmas disease?
c. When I first heard this term...