Ebola Presentation by a student before 
Ebola in Sub-Sahara Africa
Source: http://24.media.tumblr.com/tumblr_lxgsy8RUj31r98we1o1_500.jpg
History of Ebola
•
Ebola is a virus, also called Ebola Hemorrhagic Fever
•
Named after a river in the Democractic Republic of the Congo, formerly known as Zaire, in Africa, where it was first recognized in 1976.
•
It belongs to a family of RNA viruses called Filoviridae
•
Four identified subtypes in Africa: Zaire, Sudan, Ivory Coast and
Bundibugyo, each named after the region in which they occurred
Budding from host’s cells
Long, branched filaments Source: http://www.thelancetstudent.com/wp-content/uploads/2010/11/Figure-2-Model-of-Ebola-virus-pathogenesis.jpg
Pleomorphic Shape
Ebola Description
Causes severe, often fatal hemorrhagic fever in humans with fatalities ranging from
50% to 90%
Death usually occurs from shock within 6-16 days from the time of onset.
Its extreme pathogenicity classifies it as a biosafety level 4 agent.
Abrupt flu-like symptoms: fever, headache, joint and muscle aches, sore throat, and weakness, diarrhea, vomiting, and stomach pain.
The virus quickly progresses to massive hemorrhaging of internal organs, along with bleeding into the GI tract, from the skin, and even from injection sites as the clotting ability of the blood is diminished.
It then produces lesions in the liver, kidney, and spleen with areas of necrosis on the organs and the lymph nodes.
Worldwide, there have been approximately 1,800 infections and 1,400 deaths since
1976 with nearly all of them occurring in Sub-Sahara Africa.
Virus Strains
All strains are similar in shape but have different gene sequences and different properties. They all produce hemorrhagic fever, ultimately resulting in death
Zaire
Native to Africa
Causes illness in humans and primates (monkeys)
Highest rate of outbreaks and therefore, highest fatality rate
Sudan
Native to Africa
Causes illness in humans and primates (monkeys)
Ivory Coast
Native to Africa
Source: http://24.media.tumblr.com/tumblr_lxgsy8RUj31r98we1o1_500.jpg
History of Ebola
•
Ebola is a virus, also called Ebola Hemorrhagic Fever
•
Named after a river in the Democractic Republic of the Congo, formerly known as Zaire, in Africa, where it was first recognized in 1976.
•
It belongs to a family of RNA viruses called Filoviridae
•
Four identified subtypes in Africa: Zaire, Sudan, Ivory Coast and
Bundibugyo, each named after the region in which they occurred
Budding from host’s cells
Long, branched filaments Source: http://www.thelancetstudent.com/wp-content/uploads/2010/11/Figure-2-Model-of-Ebola-virus-pathogenesis.jpg
Pleomorphic Shape
Ebola Description
Causes severe, often fatal hemorrhagic fever in humans with fatalities ranging from
50% to 90%
Death usually occurs from shock within 6-16 days from the time of onset.
Its extreme pathogenicity classifies it as a biosafety level 4 agent.
Abrupt flu-like symptoms: fever, headache, joint and muscle aches, sore throat, and weakness, diarrhea, vomiting, and stomach pain.
The virus quickly progresses to massive hemorrhaging of internal organs, along with bleeding into the GI tract, from the skin, and even from injection sites as the clotting ability of the blood is diminished.
It then produces lesions in the liver, kidney, and spleen with areas of necrosis on the organs and the lymph nodes.
Worldwide, there have been approximately 1,800 infections and 1,400 deaths since
1976 with nearly all of them occurring in Sub-Sahara Africa.
Virus Strains
All strains are similar in shape but have different gene sequences and different properties. They all produce hemorrhagic fever, ultimately resulting in death
Zaire
Native to Africa
Causes illness in humans and primates (monkeys)
Highest rate of outbreaks and therefore, highest fatality rate
Sudan
Native to Africa
Causes illness in humans and primates (monkeys)
Ivory Coast
Native to Africa
References: democratic republic of congo, 2007. Vector Borne and Zoonotic Diseases (Larchmont, N.Y.), 9(6), 723; 723-728; 728. National Academy of Sciences - PNAS, 94(26), 14764.