Dolly the Sheep

Topics: Cloning, Dolly, Ian Wilmut Pages: 3 (1103 words) Published: May 2, 2013
Dilpreet Phangureh
Period 4 ; Bioligy
Dolly the Sheep Essay

The Most Amazing Sheep!
A major scientific achievement was done at the Roslin Institute because the cloning of a sheep was successful. The female sheep cloned was the first ever mammal to be cloned with an adult somatic cell, using nuclear transfer and it was named Dolly [1]. She was cloned by Ian Wilmut, Keith Cambell, and some colleagues. She was born on the fifth of July in 1996 and she lived until she was the age of 6. She has been called “The Worlds Most Famous Sheep” by BBC news [1]. Overall Dolly was a clone or a biological twin of her mother and she had a pretty unique life.

The way Dolly was created is that Wilmut and his colleagues transplanted a nucleus from a mammary gland cell of a Finn Dorsett sheep into the enucleated egg of a Scottish blackface ewe. The nucleus-egg combination was stimulated with electricity to fuse the two and to stimulate cell division. The new cell divided and was placed in the uterus of a blackface ewe to develop. Dolly was born months later. This process is called Nuclear Transfer. This strategy that they used took them 276 attempts before the outcome could come out right [2]. Overall these are the steps that took place to create Dolly.

The reason why they created Dolly is because the researchers at the Roslin Institute wanted to get new ways to produce medicine and get a better understanding of development and genetics. Dolly was produced as a part of a research at the institute to produce medicine in milk of farm animals. Researchers have now managed to transfer human genes that produce useful proteins into sheep and cows, so that they can produce, for instance, the blood clotting agent factor IX to treat haemophilia or alpha-1-antitrypsin to treat cystic fibrosis and other lung conditions [5]. These are the reasons why we created Dolly.

Dolly started her life in a test tube and then ended up as a biological twin of her mother due to Nuclear...
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