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Cushing's Disease Research Paper

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Cushing's Disease Research Paper
Topic: Cushing’s disease
Title: What is there to know about Cushing’s Disease?
Group Number: No. 6
Identification of Group Members:
What is there to know about Cushing’s disease?
What is Cushing’s disease?
The Cushing’s disease was first describe by a neurosurgeon named Harvey Cushing in the year 1912 (JB Lippincott, (1992)). The disease also known as Tertiary or Secondary Hypercortisolism (Minnie G: Lanzino, Giuseppe: Maartens, Niki F.; Laws, Edward R. (2002)) is a condition in which the steroid hormone Cortisol is produced excessively. The excessive production of cortisol occurs when there is a benign (non-cancerous) tumor is formed at the anterior of the pituitary gland. This leads to the secretion of Adrenocorticotrophic Hormone (ACTH). ACTH is normally produced by the pituitary gland, and causes the stimulation of the adrenal glands resulting in the production of cortisol also known as the stress hormone (http://pituitary.ucla.edu/cushings-disease).
Identifying Cushing’s disease
Identifying the signs and symptoms of Cushing’s disease include but are not limited to weight gain/obesity; purple stretch marks (breast, arms, abdomen and thighs); red cheeks; rounding of face; excessive hair growth; weakness/fatigue; menstrual disorders/low levels of testosterone; uncontrolled …show more content…
Some diagnostic tests used to identify Cushing’s disease are; Urine Test (24 hour urinary free cortisol test); Blood and Salivary Serum Cortisol Test; Dexamethasone Suppression Test /DST (used to assess adrenal gland function); Bilateral Inferior Petrosal Sinus Sampling Test (Drainage of the pituitary gland) (Nieman, L.K.; Ilias, I. (2005)); Imaging Test (a computerized tomography scan of the pituitary gland done in order to identify abnormalities)
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