This article is investing the effects of speed of the action potential across many neurons through investigating two diseases and performing related lab simulations. Multiple sclerosis and epilepsy are the two disease which are investigated and through the use of Neurons in Action lab simulations, we saw the effects that demyelination and channelopathy can have. As my hypothesis guessed, demyelination is the main cause of multiple sclerosis and channelopathy is the main cause of epilepsy.
Introduction
The nervous system is susceptible to many disease and disorders. Nervous system degenerative diseases are those where neurons, parts of neurons, or any part of the nervous system become damaged and die. The purpose of this study …show more content…
Starts at -75mV and ends up at 125mV staying constant at 125mV.
4) It is similar I that the charge becomes more positive before reaching a maximum. However, the changes are much less pronounced, and, with the addition of leak channels, the membrane can repolarize after the stimulus current has ended. The graph shows the Mv going from -70 to -7 to -50 (and still decreasing).
5) This graph has three spikes (the second being slightly less drastic, and the third being very slight). One from -65mV to 50mV to -73mV followed by the other from -65mV to 30mV to -73mV. The third spike looks similar to the graph in #4. The voltage-gated channels have an inactivation gate for sodium which closes at specified mV and the membrane repolarizes before initiating another action potential.
Equilibrium Potential
1) Because there are no sodium …show more content…
The Vm rapidly depolarizes, then slowly curves upward (depolarizes) before the graph line becomes almost vertical followed by steadily repolarizing and, lastly, hyperpolarizing. Because this is the way an action potential works.
B. The currents are almost identical reflections except for, at the beginning of sodium influx, there is a drastic influx spike from about 0.7ms to 1.3ms and -44mV to 45mV.
C. Sodium conductance has a sharp spike (almost vertical line to a steady decline, reaching a top of approximately 0.034), however potassium (which peaks at 0.013) is a gentle rise and decline. Sodium conductance peaks at the same time as the membrane voltage. The potassium conductance begins to increase at about 0mV. The sodium conductance begins to increase at -34mV. Sodium movement is much higher at the beginning. Potassium is gradual from middle to end.
D. 3.8ms to 5ms (end of graph). Sodium current is reaching zero, then stays at zero as driving force reaches and maintains zero current as well.
2)
A. No question in this