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A Case-Control Study

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A Case-Control Study
REVIEW QUESTIONS FOR CHAPTER 10 1. A case-control study is characterized by all of the following except:
a. It is relatively inexpensive compared with most other epidemiologic study designs
b. Patients with the disease (cases) are compared with persons without the disease (controls) c. Incidence rates may be computed directly d. Assessment of past exposure may be biased e. Definition of cases may be difficult

2. Residents of three villages with three different types of water supply were asked to participate in a survey to identify cholera carriers. Because several cholera deaths had occurred recently, virtually everyone present at the time underwent examination. The proportion of residents in each village
…show more content…
Analysis of previous research in different places and under different circumstances to permit the establishment of hypotheses based on cumulative knowledge of all known factors

c. Obtaining histories and other information from a group of known cases and from a comparison group to determine the relative frequency of a characteristic or exposure under study

d. Study of the incidence of cancer in men who have quit smoking e. Both a and c

4. In a study begun in 1965, a group of 3,000 adults in Baltimore were asked about alcohol consumption. The occurrence of cases of cancer between 1981 and 1995 was studied in this group. This is an example of:

a. A cross-sectional study b. A concurrent cohort study c. A retrospective cohort study d. A clinical trial e. A case-control study 5. In a small pilot study, 12 women with endometrial cancer (cancer of the uterus) and 12 women with no apparent disease were contacted and asked whether they had ever used estrogen. Each woman with cancer was matched by age, race, weight, and parity to a woman without disease. What kind of study design is this?

a. Concurrent cohort b. Retrospective cohort c.
…show more content…
In a study of a disease in which all cases that developed were ascertained, if the relative risk for the association between a factor and the disease is equal to or less than 1.0, then:

a. There is no association between the factor and the disease b. The factor protects against development of the disease c. Either matching or randomization has been unsuccessful
d. The comparison group used was unsuitable, and a valid comparison is not possible
e. There is either no association or a negative association between the factor and the disease

Questions 3 and 4 are based on the information given in the following table.
In a small pilot study, 12 women with uterine cancer and 12 with no apparent disease were contacted and asked whether they had ever used estrogen. Each woman with cancer was matched by age, race, weight, and parity to a woman without disease. The results are shown below:

3. What is the estimated relative risk of cancer when analyzing this study as a matched-pairs study? a.

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