Practice Questions

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1. Which of the following is NOT true regarding the EPP?

A. The EPP is a graded potential needed to reach threshold B. The EPP is the direct result of voltage-gated Na+ channels opening C. The EPP occurs in the post-synaptic membrane and is not an action potential D. To generate an EPP, ACh acts as the neurotransmitter involved in skeletal muscle contraction E. Two of the choices above are NOT true.

2. A person is being treated at a local clinic with an acetyl cholinesterase inhibitor drug for a skeletal muscle disorder (Acetyl cholinesterase breaks down ACh). How will this person present after long-term treatment with this drug?

A. The person will experience increased muscle strength due to increased amounts of ACh being released form motor neurons B. The person will experience increased muscle strength due to increased levels of ACh at the neuromuscular junction C. The person will experience increased muscle strength due to increased numbers of ACh receptors on the muscle tissue D. The person will experience increased muscle strength due to the increased flow of ACh through the channels E. Both choices A and B are true

3. A person mistakenly overdoses on a drug that worked by poisoning all of his Na+K+ pumps on the cell membranes. As a smart physiology student, you know that Na+Ca++ exchangers also exist on cell membranes near the Na+K+ pumps. These Na+Ca++ exchangers actually rely on functioning Na+K+ pumps in order for them to work. How would this person present at the emergency room?

A. He would have decreased muscle contraction due to increased extracellular Ca++ levels B. He would have decreased muscle contraction due to increased intracellular Ca++ levels C. He would have increased muscle contraction due to increased extracellular Ca++ levels D. He would have increased muscle contraction due to increased intracellular Ca++ levels
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