BIOAP 458, 2012 Name: _______________________ Raw Score: ________/ 102, ________% PROBLEM SET 7 Cardiac Electrophysiology 1) (8 pts.) Match the most appropriate pairs _F__ AV node (atrioventricular node) _E__ gap junctions _G__ action potential generated by ventricular myocytes _H__ functions as the pacemaker of the whole heart _D__ calcium _C__ Bachmann’s bundle _A__ Bundle of His _B__ action potential generated by pacemakers

Prof. Beyenbach VRT 8014

A. ventricular conduction system that distributes the action potential arriving at the AV node B. slow response action potential C. mediates the atrial action potential from right to left atrium. D. primary mediator of excitation-contraction coupling E. eliminate the need for synaptic transmission in ventricular cardiomyocutes F. electrical connection between right atrium and right ventricle G. fast response action potential H. sinoatrial node

2) (6pts.) Find the most appropriate match describing the function of the fast inward Na+ channel. _B__ channel is closed and at rest _A_ channel is open and conducting _C_ channel is closed and unresponsive (refractory) A. both m and h gates are open B. h gate is open and m gate is closed C. both m and h gates are closed

1/5

3) (12 pts.) a) (4 pts.) Draw the action potential of a pacemaker cell (slow response) as a function of time (solid line), identify the phases 0 through 4 and indicate the ionic currents dominating these four phases

b) (8 pts.) Complete the table to indicate the dominant ion and inward or outward current Phase 0 2 3 4 Dominant ion Ca Ca K K, Na, leak Inward/outward current inward current reduced inward current outward current K, reduced outward K current Na, funny inward current Leak, increased leak current

4) (14 pts) Find the appropriate match D_ shortly before the P wave A_ between P and Q B_ QRS complex C_ increased P-R interval G_ T-wave F_ not life threatening E_ occasional P without QRS A. cardiac impulse travels from SA node...

...Week 7 (12) The Instruments of Trade Policy Chapters 9
Problemset
Exercise 7.1
Use your knowledge about trade policy to evaluate each of the following statements:
a. “An excellent way to reduce unemployment is to enact tariffs on imported goods.”
b. “Tariffs have a more negative effect on welfare in large countries than in small countries.”
c. “Automobile manufacturing jobs are heading to Mexico because wages are so much lower there than in the United States. As a result, we should implement tariffs on automobiles equal to the difference between US and Mexican wage rates.”
Exercise 7.2
Home and Foreign produce and consume wheat.
a) Assume the demand for wheat in Home is: D = 100 - 20P
And the supply of wheat in Home is: S = 20 + 20P.
Numerically calculate the demand equation for imported wheat in Home. Draw the corresponding curve. What is the price of wheat in Home if there is no trade with Foreign?
b) Now add Foreign. The demand for wheat in Foreign is: D* = 80 – 20P, while the supply of wheat in Foreign equals S* = 40 + 20P.
Numerically calculate the supply equation for wheat exported by Foreign. Draw in the corresponding curve in the figure you drew for a). What is the price of wheat in Foreign if there would be no trade with Home?
c) Now assume that Home and Foreign start trading wheat. There are no costs of transport. Calculate the equilibrium price of wheat in case of open-border trade. What is the...

...FBE 421 Prof. Briggs ProblemSet #1
Please print out this document and clearly handwrite your answers to each of the questions below in the space provided. Show all your work accordingly.
A. Calculate LTM (a) Revenue and (b) Net Income for Costco Wholesale (COST) using their latest financial statements as of 3Q2011.
77946+60737-53821=84,862 MM Revenue 1303+984-871= 1,416 MM Net-income
B. Calculate Costco’s LTM (a) EBIT and (b) EBITDA.
2077+1677-1389=2,365 MM EBIT (2077+795)+(1677+582)-(1389+549)= 3192 MM EBITDA
Name: Student ID:
￼1.
￼C. Calculate Costco’s (a) Market Cap, (b) Total Debt and (c) Enterprise Value as of 3Q2011.
a) 437,735,000 * 85.07 = 37.238 Bn
b) 1+900+1,247=2.148 Bn
c) 37.238+2.148+.578 (minority interest)-4.082= 35.882 Bn (35,882 MM)
D. Calculate Costco’s (a) EV/Revenue and (b) EV/EBIT multiples.
a) 35,882/84,862=.42x b) 35,882/2,365=15.17x
2. Explain the differences between a firm’s (a) market value, (b) enterprise value, and (c) book value.
a) Market value, otherwise known as market capitalization, is the current value of the firm’s common equity on the open market. This is the value necessary to buy the entire firm’s equity.
b) Enterprise value is the value of all the claims on the firm’s capital structure less cash. This includes the value of equity, preferred stock, debt, and minority interest less cash. This is the value necessary to purchase the entire firm.
c) Book value is the value of a firm’s equity...

...Week 7ProblemSet
Chapter 26 (page 903):
1. Answer the following questions:
a. What is the difference between a firm’s cash cycle and its operating cycle?
b. How will a firm’s cash cycle be affected if a firm increases its inventory, all else being equal?
c. How will a firm’s cash cycle be affected if a firm begins to take the discounts offered by its suppliers, all else being equal?
4. The Greek Connection had sales of $32 million in 2012, and a cost of goods sold of $20 million. A simplified balance sheet for the firm appears below:
THE GREEK CONNECTIONBalance SheetAs of December 31, 2012 (in $ thousand) |
Assets | Liabilities and Equity |
CashAccounts receivableInventory | $ 2,000 3,950 1,300 | Accounts payableNotes payableAccruals | $ 1,500 1,000 1,220 |
Total current assets | $ 7,250 | Total current liabilitiesLong-term debt | $ 3,720 3,000 |
Net plant, property,and equipment | $ 8,500 | Total liabilitiesCommon equity | $ 6,720 9,030 |
Total assets | $ 15,750 | Total liabilities and equity | $ 15,750 |
a. Calculate The Greek Connection’s net working capital in 2012.
Net working capital = current assets - its current liabilities
= $7,250 - $3,720 = $3,530
b. Calculate the cash conversion cycle of The Greek Connection in 2012.
The cash conversion cycle (CCC) is defined as
CCC = Accounts Receivable Days + Inventory Days − Accounts Payable Days
Accounts Receivable Days = 3,950,000/(32,000,000/365) = 45.054687...

...Me1
ProblemSet #2
The US College Enrollment and the “Third Law of Demand”
A theorem proposed by Professors Alchian and Allen in their text, University Economics (1964) has had several rebirths of interest in the literature. The so-called “third law of demand,” or “relative price theorem,” holds that a fixed cost added to a good of varying quality causes the consumer to prefer the category considered of higher quality to the lower.
Recently a number of studies, keeping this theorem in mind have looked into a relationship between the ratio of public to private enrollment and unemployment in cross-sectional as well as in time series data. Part of the full cost of participating in higher education is foregone employment income. In their regression model, these studies have regressed the public/private ENROLLMENT RATIO (as an indicator of relevant demand) against UNEMPLOYMENT RATES (as an indicator of cost) as well as a number of variables designed to account for “other things” which tend to vary at the same time, such as income, financial aid and tuition ratios. Tuition ratio is typically specified as the ratio of the full cost (including forgone employment income) of public higher education (Pa) to private higher education (Pb), where Pa is less than Pb.
In Table 1, below, a cross-sectional model reveals the relationships between relative education demands by public and private university students (as measured by state level ENROLLMENT...

...Class Meets:
MW, Rawls 1011. 7:30-8:45 am (section 1), 9-10:15 am (section 2).
Contacts:
Professor: Chong Xiang
Office: KRAN 405
Hours: Tuesday 3-4 pm & Wednesday 12:30-1:30 pm.
Phone: 494-4499 e-mail: cxiang@purdue.edu
TA: Hyojung Lee
Office: KRAN 515
Office Hours: Tuesday 10:30-11:30 am & Thursday 10:30-11:30 am.
Phone: 494-4496 email: lee485@purdue.edu
TA: Kan Yue
Office: KRAN B024A
Office Hours: Monday 12 noon-1 pm &Tuesday 9-10 am.
Phone: 496-1458 email: kyue@purdue.edu
Course goal: We provide a broad overview of the microeconomic aspects of the international economy. We emphasize the development of analytical tools. We also show how we can apply these tools to questions with real-world relevance.
Prerequisites:
Econ 251, Econ 252 (Principles of Microeconomics, Principles of Macroeconomics)
Textbook:
1. Feenstra and Taylor, “International Trade”, 2nd Edition. We follow the textbook very closely in class and cover about 70% of its contents.
2. Yeaple, Study Guide for Feenstra and Taylor’s International Trade, 2nd Edition. We take many practice problems from the Study Guide.
5 copies of the textbook (2nd edition) and 5 copies of the Study Guide (2nd edition) are on reserve at Parrish (the management-and-econ library).
Distribution of homework and other materials:
Katalyst -...

...EC 109
Autumn 2011
Dr. Mani
ProblemSet 2
Due Date: Oct31, Monday – between 9 & 11 AM in room S 2.132
Please keep a copy of your assignment and show all your work clearly.
(1) Mr. J. Bond, a retired movie actor, consumes only grapes and the composite good Y (i.e. price of Y is £1). His income consists of £10000 a year from his investment fund plus the proceeds of whatever he sells of the 2000 bushels of grapes he harvests annually from his vineyard in Tuscany. Last year, grapes sold at £2 per bushel and Bond consumed all 2000 bushels of his grapes, in addition to 10,000 units of Y. This year, the price of grapes is £3 per bushel (and the price of the composite good Y is the same as before). If Bond has well-behaved preferences, will his consumption of grapes this year be greater than, less than or the same as last year’s? How about his consumption of the composite good? (Hint: Graph both years’ budget constraints and think about whether last year’s bundle is affordable to Mr. R).
(2) Suppose Carmela’s income is £100 per week, which she allocates between sandwiches and books. Sandwiches cost £2 each. Books cost £10 each if she purchases between 1 and 5 books. If she purchases more than 5 books in a week, the price falls to £5 for the 6th book and all subsequent books. Draw the budget constraint. Is it possible that Carmela might have more than...

...the force they exert on each other, and the electric field at a point midway between them.
Given: Formula:
k = 9 x 109 Felec = k q1 q2 /r2
q1 = 6 x 109 C
q2 = 4 x 109 C
r = 3 m
Felec = (9 x 109)(6 x 109)(4 x 109)/32
Felec = 24 x 109 N
6. A 50 cm piece of nichrome wire is used in a home heating element. The cross sectional area of the wire is 0.05 mm2. What is the resistance of the heating element? If it is operated on household current (110 V), how much heat is produced in one minute? ( Nichrome = 100 x 10-8 Ω-m)
Given:
A = .05 mm2 = (.05)(10-3)2 = .05 x 10-6 m2 , and
L = 50 cm = .5 m .
Formula:
R = ρL/A
Solution:
R = (100 x 10-8)(.5)/(5 x 10-8)
R = 10 ohms
7. A nine volt battery supplies power to a cordless curling iron with a resistance of 18 ohms. How much current is flowing through the curling iron?
Given:
R = 18 ohms Formula:
V = 9 volts I = V/R
Solution:
I = 9 volts / 18 ohms
I = 0.5 A
8. Given:
V = 9 v
R1 = 3 ohms
R2 = 3 ohms
R3 = 3 ohms
Formula:
I = V/(R1 + R2 + R3)
Solution:
I = 9/(3 + 3 + 3)
= 9/9
I = 1 A
9.
The total current in this circuit is 12 A.
Determine:
a) the voltage passing through each resistor
V = V1 = V2 = V3 = 24 V
b) the total resistance
1/Rtotal = 1/R1 + 1/R2 + 1/R3
Rtotal = Vtotal/ Itotal = 24/12 = 2 Ω
c) the value of resistor R3
1/R3 = 1/Rtotal - 1/R1 -1/R2 = (1/2) – (1/12) – (1/4) =...

...GENERAL BIOCHEMISTRY
ProblemSet No. 1
Answered by: Andrea Rose A. Fajardo of BSFT 2-1N
1. Calculate the pH of a dilute solution that contains a molar ratio of potassium acetate to acetic acid (pKa=4.76) of:
a. 2:1
pH = 4.76 + log[2]/[1]
= 4.76 + 0.3010
= 5.06
b. 1:4
pH = 4.76 + log[1]/[4]
= 4.76 + (-0.6021)
= 4.16
c. 6:5
pH = 4.76 + log[6]/[5]
= 4.76 + 0.0792
= 4.81
d. 2:3
pH = 4.76 + log[2]/[3]
= 4.76 + (-0.1761)
= 4.58
e. 9:1
pH = 4.76 + log[9]/[1]
= 4.76 + 0.9542
= 5.71
2. A buffer contains 0.01mol of lactic acid (pKa=3.86) and 0.05mol of sodium lactate per liter.
a. What is the resulting pH of the buffer?
pH = 3.86 + log[0.05]/[0.01]
= 3.86 + 0.6990
= 4.56
b. Calculate the change in pH when 5mL of 0.5M HCl is added to 1L of buffer.
5mL of 0.5 mol/L
5mL * 1L/1000mL = 0.005L
0.005L * 0.5 mol/L = 0.0025mol
NaC3H5O3 = 0.05mol - 0.0025mol = 0.0475
C3H5O3 = 0.01mol - 0.0025mol =0.0075
pH = 3.86 + log[0.0475]/[0.0075]
= 3.86 + 0.8016
= 4.66
• 4.55-4.66 = 0.11 is the change in pH
c. What pH change would you expect if you added the same quantity of HCl to 1L of pure...

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