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Advances in Applied Science Research, 2011, 2 (2): 260-264
ISSN: 0976-8610 CODEN (USA): AASRFC
Antifungal activity of some plant extracts against Clinical Pathogens Abhishek Mathur*1, Ravinder Singh1, Sajad Yousuf1, Aprajita Bhardwaj1, Satish K. Verma1, Pradeep Babu2, Vinay Gupta2, GBKS Prasad3 and V.K. Dua4 Sai Institute of Paramedical & Allied Sciences, Dehradun (U.K), India Uttarakhand Technical University, Dehradun (U.K), India Jiwaji University, Gwalior (M.P), India National Institute of Malaria Research, Hardwar (U.K), India ______________________________________________________________________________ ABSTRACT The antifungal activity and minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as hydro-alcohol (50 % v/v) and hexane of plants traditionally used as medicines as Valeriana jatamansi (Sugandhbala), Coleus barbatus (Pathar choor), Berberis aristata (Kingore), Asparagus racemosus (Satrawal), Andrographis paniculata (Kalmegha), Achyranthes aspera (Latjiri), Tinospora cordifolia (Giloei), Plantago depressa (Isabgol) were evaluated against Aspergillus niger and Candida albicans. Hydro-alcoholic extracts of all the plants were found to have maximum antifungal activity in comparison to hexane extracts. Hydroalcoholic extracts of Andrographis paniculata and Achyranthes aspera showed maximum potency against Aspergillus niger and Candida albicans at highest MIC value of 0.5 and 0.3 mg/ml respectively. Hexane extracts of Andrographis paniculata showed highest MIC value of 0.7 mg/ml against Aspergillus niger. Key words: Hydroalcoholic extracts, hexane extracts, clinical pathogens, antifungal activity. ______________________________________________________________________________ INTRODUCTION In developing countries and particularly in India low income people such as farmers, people of small isolated villages and native communities use...
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