Preview

How Does Stress Affect The Immune System

Good Essays
Open Document
Open Document
604 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
How Does Stress Affect The Immune System
How does stress affect the immune system

The immune system is designed to defend the body against millions of antigens that would otherwise invade it. None of these things are able to get in when your immune system is working efficiently, but the moment your immune system stops functioning properly, the opportunity for antigens to attack is available.
Kiecolt-Glaser (1984) carried out a natural experiment investigating whether the stress of short-term stressors had an effect on immune system functioning in medical students. Blood samples were taken one month before and during exam period itself. Immune system functioning was assessed by measuring NK cell activity in the blood samples. Participants also completed a questionnaire to measure other life stressors they were experiencing.
They found that NK cell activity was significantly reduced in the second blood sample compared to the sample taken one month before. This suggests that short-term stressors reduce immune system functioning thus increasing vulnerability to illness. Kiecolt-Glaser also found that the highest level of loneliness had the lowest NK cell activity.
Exam-related immune changes have also shown to have a dramatic effect on the rate at which wounds heal. Marucha (1998) inflicted a ‘punch biopsy’ in the mouth of the
…show more content…
Marital relationships can be stressful, as can separation from a marital partner. Kiecolt-Glaser (2005) tested the impact of interpersonal conflict on wound healing. She found that blister wounds on the arms of married couples healed more slowly after they had a discussions which were conflicting rather than supportive. Kiecolt-Glaser (1987) compared women separated from their partners with matched married controls. They found poorer immune system functioning in women who had separated during the last

You May Also Find These Documents Helpful

  • Satisfactory Essays

    The field of PNI is not without controversy. One of the debatable topics is the causal relationship between stress, depression and immune response. Depression has been implicated in causing behavioral changes in people with major depressive disorder. Some of these lifestyle changes can be profound, such as, not eating, drug abuse, or disturbed sleep patterns. Some argue that it really is these "lifestyles" which is the culprit in reduced immune functioning. Having bad nutritional habits could starve the body of necessary nutrients to maintain high levels of white blood cells. As a result, the immune system downgrades its functioning and the person becomes more prone to diseases or inflammatory.…

    • 322 Words
    • 2 Pages
    Satisfactory Essays
  • Better Essays

    The Inflammatory Response

    • 1243 Words
    • 5 Pages

    The body is designed to defend itself against invading bacteria, and infection. The skin and mucous membranes are the first line of defence, the invasion of foreign bacteria can pass this first line of defence and immediately triggers the second line of defence. The second line of defence is the inflammatory response (McCance & Huether, 2009). The mechanism of the inflammatory response is to protect the injured site by killing the agent responsible, limiting its effects on the rest of the body and initiating the healing process (Porth, 2007).…

    • 1243 Words
    • 5 Pages
    Better Essays
  • Good Essays

    During strenuous times, our body undergoes many physiological changes in order to aid our survival, and this is an inherited function (Canon’s ‘fight or flight’ theory). Stress in small doses, in fact is needed and useful to humans, however long term stress can take its toll on the body. The General Adaptation Syndrome (GAS) model was developed by Selye to explain the effects of exposure to stressor. The GAS model consists of these 3 stages; Alarm – when our HPAC and SAM pathways are activated, causing stress related hormones like adrenaline and cortisol to be releases into blood, which in turn, converts to glucose, giving the body a sudden surge of energy, allowing ‘fight or flight’ like behaviours, until the stressor is gone and the parasympathetic nervous pathway activates, allowing us to calm down. Resistance – When the stressor remains however the person appears unaffected on the outside, but internally the stress related effects are occurring, e.g. stress hormones still being released and a continued elevation in heart rate. The resistance stage can harm health, as the immune system is not as effective. However the body attempts to resist disease. Further stressors make this much harder. Exhaustion – stressor still persists (and would now be referred to as Chronic stress) and Selye claimed that the body’s defences can no longer cope with the demands that are made, resources are drained, causing a drastic fall in blood sugar levels, and our adrenal glands no longer function properly. However this is inaccurate, which is a criticism of the GAS model, as while the body is ‘exhausted’ in terms of full ability, it could still perform if immediate action and release of energy was needed. It is also believed that many of the long lasting effects of raised stress hormones is what causes stress related illnesses, rather than the body’s sources being depleted. The study lacks ecological…

    • 968 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Patient Zero Lab Report

    • 1353 Words
    • 6 Pages

    The Immune system is one of the most important parts of the human body. Its role is to protect us from outside dangers such as pathogens and disease and to keep the body healthy. The immune system protects the body from disease by having a complex system of organs and cells to keep the body safe. The first barrier of the immune system and of the body is the skin which keeps out pathogens from entering the body, but if there is a cut in the body, the skin can no longer defend against the pathogen, so next comes inflammation which helps to limit the spread of the disease by causing swelling and a large amount of white blood cells to go to the injured parts of the body. Another really important…

    • 1353 Words
    • 6 Pages
    Good Essays
  • Satisfactory Essays

    Fourth, it can increase or boost your immune system. Dr. Shelton (2012), said that when the body responds to stress, it prepares the body for the possibility of injury or infection. One response of the body to stress is the “fight or flee”, it keeps the body intact despite the situation, this is because the body produces certain chemicals which…

    • 204 Words
    • 1 Page
    Satisfactory Essays
  • Satisfactory Essays

    Chapter 14 talks about the immune system and how it protects us from dangerous invaders. Immunizing agents and allergenic extracts are biologics. They are chemical agents that produce biological responses inside the body. Vaccinations are highly effective compared to other drugs, the history of smallpox can prove of it. When a microorganism enters the body, lymphocytes are activated to provide antibodies. Lymphocytes attempts to resist infection by invading the pathogens with physical and chemical attacks. Immunity is the ability to infection through activation of specific defenses. The blood contains T cells, B cells and natural killer cells to directly attack invaders, attack infected cells and release antibodies. There is active immunity…

    • 142 Words
    • 1 Page
    Satisfactory Essays
  • Better Essays

    The immune system is responsible for protecting the body from numerous threats that can cause disease. If the immune system is damaged in any way, it becomes more likely that the immune system cannot fight off these potential threats that can cause harm to the…

    • 1718 Words
    • 7 Pages
    Better Essays
  • Good Essays

    What is the inflammatory response? According to "Definition of Inflammatory Response" (1996-2014), it is “a fundamental type of response by the body to disease and injury, a response characterized by the classical signs of ‘dolor, calor, rubor, and tumor’ -- pain, heat (localized warmth), redness, and swelling.” A very important part of the body’s defense system is inflammation; this is when there is a crucial protective response by the body’s system of self-defense (Definition of Inflammatory Response, 1996-2014). Acute inflammation lasts only a few days, it is short-lived whereas chronic inflammation lasts longer; like weeks, months, and maybe even years. When the inflammatory process is involved in healing and repair it may cause tissue damage. Inflammation can play a role in many disorders; for example Alzheimer’s, asthma, diabetes, osteoporosis, and even HIV/AIDS.…

    • 944 Words
    • 4 Pages
    Good Essays
  • Satisfactory Essays

    Prolotherspy

    • 904 Words
    • 3 Pages

    III. Inflammation is a localized tissues level response that tends to limit the spread of an injury or infection. The process of inflammation is initiated by the cells which are already in the tissue, which are mostly dendritic cells, macrophages, kupffer cells, and mastocytes. Histocytes and mast cells. Cells that prevent any infection can mostly be white blood cells. They are neutrophils, bands, eosinophils, basophils, monocytes and lymphocytes. Each of them will fight the infection in a different way. For example, neutrophils is one of the body’s main defense against bacteria. They kill the bacteria by ingesting them. Bands are immature neutrophils. When a person has parasites or an allergic reaction eosinophils kills it. Another white blood cell that fights allergies is the basophil by releasing histamine and heparin. Monocytes enter the tissue itself and ingest bacteria throughout the body. These cells can also destroy damaged dead cells. The monocytes and neutrophils can kill invading organism by squeezing the opening of the blood vessel. That kills bacteria by surrounding it and digesting them with enzymes. There is also a two phase that responds to injury and restores normal function. They are the vascular and cellular. To remove damaged tissue and make new tissue it does it by destroying or neutralizing harmful agents. Mixed with the repair process that replaces the damage tissues. The reaction of vascularized tissue to injury is characterized by the…

    • 904 Words
    • 3 Pages
    Satisfactory Essays
  • Powerful Essays

    Inside your body there is an amazing protection mechanism called the immune system. We do not notice it when it is working as it should be, but we do notice when it is not. Your complex immune system is made up of many components, cells and systems working together to serve and protect your health and well…

    • 1180 Words
    • 5 Pages
    Powerful Essays
  • Good Essays

    Natural Acquired Immunity

    • 394 Words
    • 2 Pages

    If the body fails to remove all the harmful substances with the natural immunity, the stronger acquired immunity acts as a secondary defense to remove rest of the foreign substances. Exposure to any antigens is induced by specific microbial antigen infections and unique responses to specific antigen cells, thereby giving lifetime immunity to antigens. Lymphocytosis (B cells, T cells) becomes the starting point of acquired immunity. It is divided into cellular mediated immune responses (T cells) or bodily fluids (B cells). It is induced by antigen inflow and is capable of distinguishing specific antigens. As the number of antigen streams increases, the ability to increase the reaction is utilized to develop vaccines. For example, it needs to be infected once in a way to gain immunity to the mumps. It's an immune system that exists only in high…

    • 394 Words
    • 2 Pages
    Good Essays
  • Good Essays

    Worrying over a test is normal for any student. However, tests are not the only things students have to worry over. Family matters, money problems, boyfriends or girlfriends, and even the death of a loved one can add stress to an individual. As things keep adding up and the stress level keeps rising, some students may find themselves getting sick. Before the 1970’s there was no reason to believe that stress and the immune system had anything to do with each other. This relationship which was thought to be “non-existent” would soon be found to be real and affecting millions of people. The subject became so real in the scientific world it was given its own name psychoneuroimmunology. This obnoxiously large word is just a way of stating there are connections between psychological process, the nervous system, and the body’s immune system (507).…

    • 676 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Stress Is Beneficial

    • 990 Words
    • 4 Pages

    Stress has many useful effects on our body. Some people think that stress makes you exhausted and ages you faster than normal. However, according to a research held in America, stress helps you be fresh and cheerful. In contrast to common opinion, stress renews your skin and other cells, which makes you younger and energetic .As a result, we can say that “don’t worry about aging” .All you need is stress. In another research at Stanford University, it is said that stress helps your immune system be stronger. It also speeds up the recovery process. Stress stimulates your cells and makes them faster, so you come over a disease as quickly as possible. For example, stressed people’s cuts recover fast. Stress is helpful for your immune system, because it resists against infections and increases the number of antibodies. The more antibodies you have, the healthier you are. If you are under stress, you are so lucky that you don’t have to wait a longer time to come over an illness. Stressed people’s body cells are always regenerated, so they have bright skin, and no scars. They are always energetic, younger and cheerful. Stress has also an influence on the development of an embryo. According to a study at Baltimore University in ABD, women who have a stressful pregnancy have more developed babies. The babies have also good language learning skills. If you want your baby to be skilled and developed, stress is not bad for you during the pregnancy. No matter what other people think about…

    • 990 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    This study was carried in the Ohio State University College of dentistry and published in 1998. This study began by reviewing a previous study on stress and health. This found that people undertaking a chronically stressful activity show characteristic changes in their blood chemistry and take longer to heal minor wounds than do people who are not under conditions of stress. Therefore, it addressed the effects of a commonplaces stressor, examination stress, on wound healing.…

    • 1120 Words
    • 5 Pages
    Powerful Essays
  • Powerful Essays

    Acute Inflammation

    • 4193 Words
    • 17 Pages

    [The components of the inflammatory reaction that destroy and eliminate microbes and dead tissues are capable of also injuring normal tissues. Therefore, injury may accompany entirely normal, beneficial inflammatory reactions, and the pathology may even become the dominant feature if the reaction is very strong (e.g., when the infection is severe), prolonged (e.g., when the eliciting agent resists eradication), or inappropriate (e.g., when it is directed against self-antigens in autoimmune diseases. or against usually harmless environmental antigens in allergic disorders).…

    • 4193 Words
    • 17 Pages
    Powerful Essays