Henoch-Shonlein Purpura Research Paper
Henoch-Schonlein Purpura
Henoch-Schonlein purpura, also known as HSP, is a type of vasculitis, a group of disorders that cause blood vessel inflammation. In HSP, the inflammation causes bleeding in the capillaries in the skin, joints, intestines and kidneys. Although HSP can affect anyone, it occurs most often in children between the ages of 2 and 11, affecting boys more often than girls. HSP is the most common form of vasculitis in children, with an annual occurrence of 140 cases per one million children. However, adult cases are sometimes more difficult. Skin manifestations are more variable in adults, and sometimes symptoms in adults endure longer.
The cause of the initial inflammation is still unknown, but is believed that the immune …show more content…
The treatment is usually aimed at preventing further complications, most often meaning bed rest, plenty of fluids, and acetaminophen (Tylenol, others) or nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin, others), costing on average $8 per bottle . If the kidneys are affected, medical care is generally needed, as well as long-term follow-up to prevent more-serious problems. Depending upon the severity of the kidney damage the treatments can range from steroidal drugs, such as prednisone, costing $100 per bottle without insurance, to a kidney transplant, costing $262,900 without …show more content…
People with HSP are encouraged to stay comfortable and allow for the disease to run its course. Urine tests do need to be done periodically which can be quite frustrating especially for one who a busy schedule. Since HSP does not typically affect people’s lifestyle in a major way there is only a small amount of research currently being done. The main research being done is studies to fully understand the underlying causes so they can stop the disease from developing into severe problems such as renal kidney failure. They are doing so by many clinical trials using different medications to determine which ones essentially treat the disease which will in return show what underlying factor is causing the
Henoch-Schonlein purpura, also known as HSP, is a type of vasculitis, a group of disorders that cause blood vessel inflammation. In HSP, the inflammation causes bleeding in the capillaries in the skin, joints, intestines and kidneys. Although HSP can affect anyone, it occurs most often in children between the ages of 2 and 11, affecting boys more often than girls. HSP is the most common form of vasculitis in children, with an annual occurrence of 140 cases per one million children. However, adult cases are sometimes more difficult. Skin manifestations are more variable in adults, and sometimes symptoms in adults endure longer.
The cause of the initial inflammation is still unknown, but is believed that the immune …show more content…
The treatment is usually aimed at preventing further complications, most often meaning bed rest, plenty of fluids, and acetaminophen (Tylenol, others) or nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin, others), costing on average $8 per bottle . If the kidneys are affected, medical care is generally needed, as well as long-term follow-up to prevent more-serious problems. Depending upon the severity of the kidney damage the treatments can range from steroidal drugs, such as prednisone, costing $100 per bottle without insurance, to a kidney transplant, costing $262,900 without …show more content…
People with HSP are encouraged to stay comfortable and allow for the disease to run its course. Urine tests do need to be done periodically which can be quite frustrating especially for one who a busy schedule. Since HSP does not typically affect people’s lifestyle in a major way there is only a small amount of research currently being done. The main research being done is studies to fully understand the underlying causes so they can stop the disease from developing into severe problems such as renal kidney failure. They are doing so by many clinical trials using different medications to determine which ones essentially treat the disease which will in return show what underlying factor is causing the