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Epidemiology of Ms

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Epidemiology of Ms
The Epidemiology of Multiple Sclerosis:
An in-depth Study
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Abstract
This paper examines eight journalistic articles depicting research and case studies analyzing the epidemiology of Multiple Sclerosis (MS). This in-depth analysis will explain the history and prevalence of the disease, and its impact on our society, along with a critical exploration of primary, secondary and tertiary interventions for MS along with its problematic relations with regard to the Healthy People 2010 objectives.

The Epidemiology of Multiple Sclerosis: An in-depth Study
Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system which continues to be on the increase throughout the world. A horrible and unpredictable disorder that can vary in presence from benign to partial disability to completely catastrophic as transmission between the brain and other areas of the body becomes interrupted and confused. With the onset of MS, the body’s own auto-immune system attacks the protective layer of myelin surrounding the spinal cord. Over time, lesions and scar tissue form replacing the myelin layer and thus disrupting the neurological network of nerves that go between the brain and the spinal cord (Lucchinetti et al, 2002). Over the past 100 years, approximately 300 studies have been conducted on subjects diagnosed with this debilitating disease ranging from prevalence, risk factors, degree of severity, and possible preventions (Kurtske, 2006). This paper will focus on the problems associated with MS beginning with a medical analysis, studying prevalence and incidence, intervention and the diseases’ importance and effect within the health community.
Multiple Sclerosis Research Description and Diagnosis Multiple sclerosis is an often times disabling disease which attacks the body 's



References: Healthy People 2010. Objectives and Goals. (2005). Retrieved from http://www.healthypeople.gov/About/hpfact.htm. Kurtzke, J.F. (2006). Epidemiology and Multiple Sclerosis: A personal view. Retrieved from http://www.direct-ms.org/pdf/EpidemiologyMS/EpidemiologyMS.pdf. Lucchinetti, C., Bruck, W., Parisi, J., Scheithauer, B., Rodriguez, M., and Lassmann, H. (2002). Heterogeneity of Multiple Sclerosis Lesions: Implications for the Pathogenesis of Demyelination. Annals of Neurology, 47, 707-717. Minagar, A., and Alexander, S. (2003). Blood-brain barrier disruption in multiple sclerosis. Multiple Sclerosis Journal, 9, 540-549. Retrieved from http://www.direct-ms.org/sites/default/files/Minagar%20BBB%20disruption%2003.pdf. Multiple Sclerosis: Hope Through Research. (n.d.). National Institute of Neurological Disorders and Stroke. www.ninds.nih.gov. Retrieved from http://www.ninds.nih.gov/disorders/multiple_sclerosis/detail_multiple_sclerosis.htm. Noseworthy, J.H., Lucchinetti, C., Rodriguez, M., & Weinshenker, B. (2000). Medical Progress: Multiple Sclerosis. The New England Journal of Medicine. 343. Retroeved from http://content.nejm.org/cgi/content/full/343/13/938. Williams, R., Rigby, A.S., Airey, M., Robinson, M., $ Ford, H. (1995). Multiple Sclerosis: its epidemiological, genetic, and health care impact. Journal of Epidemiology and Community Health, 49. DOI: 10.1136/jech.49.6.563. Zorzon, M., Zivadinov, R., Nasuelli, D., Dolfini, P., Bosco, A., Bratina, A., Tommasi, M.A., Locatelli, L., & Cazzato, G. (2003). Risk factors of multiple sclerosis: a case-control study. Journal of Neurological Science, 24. DOI: 10.1007/s10072-003-0147-6.

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