Preview

Animal Model Of Obesity

Satisfactory Essays
Open Document
Open Document
138 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Animal Model Of Obesity
Obesity is a major health problem and one of the leading causes of death globally. The needs of obesity care increased in last two decades. Obesity also increases the risk of diabetes, cardiovascular disorder, stroke and colon cancer. Obesity can be managed by physiological and pharmacological approach, but physiological approach getting failed by patient noncompliance. Pharmacological approach has its own advantages and disadvantages, moreover the needs of drug targets increasing to discover novel antiobesity agents. The developed a new target must be evaluated preclinically and clinically to determine its therapeutic efficacy. Objective of this review is to summarize the most commonly used animal models of obesity research. The model includes

You May Also Find These Documents Helpful

  • Satisfactory Essays

    Research into homeostasis can be applied to everyday life. For example, Doctors or Pharmaceuticals can develop medication such as special pills which specifically target centres within the homeostasis model – lateral hypothalamus and the ventromedial hypothalamus. Medication can be developed for those who are either obese or underweight. This is because levels of blood glucose have been found to affect an individuals eating behaviours and therefore their weight too. This medication which can treat obesity can help increase glucose levels which in turn activate the ventromedial hypothalamus on. This then reduces the amount the individual eats. Those who are underweight can take medication containing the hormone neuropeptide Y which will activate the lateral hypothalamus. This information is useful because obesity is such a…

    • 347 Words
    • 2 Pages
    Satisfactory Essays
  • Powerful Essays

    Hindbrain Function

    • 2339 Words
    • 10 Pages

    With obesity being a cultural syndrome in the US, there is a necessity to find solutions for it. Previous work has emphasized the importance of neuropeptides (protein neurotransmitters) in controlling obesity triggering factors such as ingestion and energy expenditure. The orexins (orexin A and orexin B) are a family of neuropeptides important in promoting physical activity, and have also recently been shown to increase energy expenditure through effects on thermogenesis. The research looks at the hindbrain signalling orexin A helps in controlling energy expenditure via thermogenesis. (Lee,…

    • 2339 Words
    • 10 Pages
    Powerful Essays
  • Good Essays

    Forskolin Research Paper

    • 525 Words
    • 3 Pages

    It has deduced by scientists at the Penn State University College of Medicine that Camp production is impaired with many obese patients. From this it points to the solution that many obese patients may benefit from Forskolin.…

    • 525 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Website Review Table

    • 509 Words
    • 3 Pages

    Search, print, weight loss drug information developed at The University of Alabama in Birmingham, table of contents…

    • 509 Words
    • 3 Pages
    Satisfactory Essays
  • Satisfactory Essays

    Over the past couple of decades, the United States adult population has become much heavier. Since 1987 through 2007, the adult population of obese or overweight people increased from 44 percent to 63 percent. This being said almost two-thirds of our adult population now falls into either the obese or overweight category. With this major increase in adults being obese or overweight is causing a major health challenge. These kinds of issues can cause many serious health illnesses, such as diabetes, hypertension, and heart disease. Direct medical spending on diagnosis and treatment of these illnesses are likely to increase with the rising obesity levels.…

    • 668 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Studies that have mapped the connections between neurons in the brain, gain insight into the regulation of appetite and metabolism. The ARC and VMH has long been thought of as satiety centers. Studies that investigate the role of the arcuate nucleus in the hypothalamus, in regulating appetite and metabolism, have targeted two chemically identified neuronal types within the ARC: anorexigenic pro-opiomelanocortin (POMC) neurons and orexigenic neuropeptide Y (NPY)/agouti-related peptide (AgRP) neurons. The melanocortin α-melanocyte stimulating hormone (α-MSH, a biologically active peptide produced in POMC neurons) serves as an agonist, whereas AgRP is an inverse agonist at the anorectic melanocortin receptors (MC3R and MC4R) in the central nervous system. NPY elicits its physiological effects via differential activity at the G-protein coupled NPY receptors (NPY1R, NPY2R, NPY4R, and NPY5R) independent of melanocortin receptors [11]. Notably, although there are only a few thousand POMC and NPY/AgRP neurons within the arcuate nucleus [7], α-MSH and NPY/AgRP released from these neurons have potent effects on food intake and metabolism, respectively.…

    • 601 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Obesity Case Studies

    • 1967 Words
    • 8 Pages

    THOMPSON, WARREN, G (2007).Treatment of obesity. [Online]. Mayo Clinic Proceedings, 82 (1), 93-102. Article from Nursing/Academic edition last accessed 19th November 2012 at:…

    • 1967 Words
    • 8 Pages
    Powerful Essays
  • Good Essays

    Obesity is an epidemic that affects people Worldwide. According to the World Health Organization, The obese population of World as a whole is approximately 1 billion people. (Croissant). “Obesity, [is] a state in which excess lipids accumulate in various body fat depots due to a chronic imbalance between energy intake and energy expenditure…” (Tan, et al). Most experts believe that one of the leading causes of obesity is overeating. In the United States, the rise in the average weight of Americans can be rooted back to [simply] consuming more calories (“The Overeating Epidemic”). Lack of exercise has been argued to be a major cause of the obesity problem.…

    • 1064 Words
    • 5 Pages
    Good Essays
  • Good Essays

    Obesity Response

    • 539 Words
    • 3 Pages

    In his article, Kentucky Town of Manchester Illustrates National Obesity Crisis, Wil Haygood talks about the obesity problem among the people of Manchester Kentucky. Haygood observes that Manchester is one of the unhealthiest places in Kentucky. However, the people of Manchester are far from eager to discuss or even acknowledge this problem. Haygood places much of the blame for the obesity problem on the local people being uneducated about the risks being obese can pose to their health, an abundance of fast food restaurants, and a lack of recreational venues. I believe that Haygood made many good and accurate observations in his article, because being from a small town similar to, and not very far from Manchester, I share many of his concerns for the people in my community.…

    • 539 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Obesity in America

    • 947 Words
    • 4 Pages

    7. Proietto, Joseph and Baur, Louise A. “10: Management of obesity.”. The Medical Journal of Australia. Editors: Donald J Chisholm and Jeffrey D Zajac. MJA 2004; 180 (9): 474-480 http://www.mja.com.au/public/issues/180_09_030504/pro10445_fm.html…

    • 947 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    Obesity in America

    • 1195 Words
    • 4 Pages

    Obesity is a complex, multifactorial, and chronic disease that requires a comprehensive medical approach to care. It is the second leading preventable cause of death in the U.S., and is associated with a large number of co-morbid conditions. Care should therefore not be seen as simply having the goal of reducing body weight, but should additionally be focused on improving overall health and quality of life.…

    • 1195 Words
    • 4 Pages
    Powerful Essays
  • Good Essays

    Essay On Obesity In America

    • 4472 Words
    • 18 Pages

    More than one-third of adults, about 37.5%, in the United States are obese (Adult Obesity Facts). A majority of the people in the country would attribute this high number of obese adults to two main factors; too much food and too little exercise. Unfortunately, there are many more factors that contribute to obesity. Those factors include lack of energy balance, inactive lifestyle, environment, genes and family history, health conditions, medicines, emotional factors, smoking, age, pregnancy, and lack of sleep. A culmination of these factors feed the increase of body fat and equate to…

    • 4472 Words
    • 18 Pages
    Good Essays
  • Better Essays

    Childhood Obesity Epidemic

    • 1319 Words
    • 6 Pages

    The medical definition for obesity is having too much body fat. Many people tend to get obesity and being overweight mixed up. Being obese is different from being overweight in that being overweight is the status of weighing too much. This weight can come from many places, such as muscle, bone, fat, and/or body water. While technically they don’t mean the same thing, they both, however, mean that a person’s weight is greater than what is considered healthy for his or her height. This social problem has become an increasingly severe medical problem dating back to the early 1960s as shown in the national nutritional surveys that have been given. Although it has been proven that genetics are a large…

    • 1319 Words
    • 6 Pages
    Better Essays
  • Good Essays

    Obesity Patient

    • 831 Words
    • 4 Pages

    Obesity is one of the most dangerous problems we face these days. As a result of the prevalence of obesity, the life expectancy of human will be lower than it is now. Obesity symptoms are weight gain and increase the amount of fat. According to World Health Organization the number of people with obesity has doubled since 1980 and in 2014 more 1.9 billion of adults were overweight, 60% of them were obese, 41 million children under the age of 5 were overweight or obese. Before the twentieth-century Obesity was rare. However, in 1997 the World Health Organization declared obesity as a global epidemic Prevalence of obesity causes many diseases. Such as diabetes and Hypertension, Cardiovascular disease, Breathing problems, PCOS, Kidney disease.…

    • 831 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    Hirsch, Jules; Leibel, Rudolph L.; Rosenbaum, Michael. "Obesity." The New England Journal of Medicine August 7, 1997. 396-407.…

    • 2740 Words
    • 11 Pages
    Powerful Essays