At some point‚ as he recalled in one interview‚ he was given a textbook on crystallography with a suggestion to read it. “I do not need to read it‚ I teach this book‚ I know what is in it” – he replied. But he was eventually distanced
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specific three dimensional arrangement of atoms in molecules is referred to as molecular geometry. We also define molecular geometry as the positions of the atomic nuclei in a molecule. There are various instrumental techniques such as X-Ray crystallography and other experimental techniques which can be used to tell us where the atoms are located in a molecule. Using advanced techniques‚ very complicated structures for proteins‚ enzymes‚ DNA‚ and RNA have been determined. Molecular geometry is associated
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The story of Rosalind Franklin is a fascinating one‚ not purely because of her work with X-ray crystallography and DNA molecules‚ but rather in large part to an exciting race between her and two Cambridge students named James Watson and Francis Crick to see who could determine the correct function of a DNA molecule. Rosalind was born in London on July 25th‚ 1920 to a wealthy Jewish banking family. Rosalind wasn’t like the other kids. While most kids loved to play pretend and girls especially were
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Introduction Rational drug design is a process essentially finding out how an infective agent works against a cell and using that information to design a drug that prevents the infective agent from being able to do what it does. Influenza viruses are continually changing into new strains. The proteins in their outer layer change continually. Our bodies learn to defend against one influenza virus‚ but the next time we are infected with an influenza virus it is different from the previous one and
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She discovered how x-rays crystallography can be used to determine the structure of proteins. She assisted Bernal as he applied the technique to pepsin‚ the first time this method was used in analyzing a biological substance. In‚ 1932 Dorothy began her career in Cambridge working in the lab of John Desmond Bernal. John Bernal was a true pioneer in the early days of X-ray crystallography‚ and was consistently pushing the boundaries of the possible ways of
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DISCIPLINE OF PHARMACEUTICAL CHEMISTRY DRUG DESIGN AND DISCOVERY BY: xxxxxxx Introduction A drug is a substance that we used mostly in our daily lives. It is a chemical substance with physiological effects when ingested or introduced into our bodies. The response produce can either be beneficial or harmful. Toxins and poisons can be classified as drugs. This report the term ‘drug’ is for medicinal or pharmaceutical purposes. Drugs used to prevent or treat diseases. Drug design
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Bibliography: * Vorvick‚ L.J. (2011). X-ray. Available: ://www.umm.edu/imagepages/1057.htm. Last accessed 11 May 2013. * Simonite‚T. (2007). Colour X-ray machine sees so much more . Available: http://www.newscientist.com/article/dn12977-colour-xray-machine-sees-so-much-more.html. Last accessed 27 May 2013. * Various Authors. (2012). Radiation Dose in X-Ray and CT Exams. Available: http://www.radiologyinfo.org/en/pdf/sfty_xray.pdf. Last accessed 11 May 2013. * Various Authors. (2013 ). Boxer
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Radiologist I. Introduction A. (Opening Device) I’m sure most of you in here have broken‚ fractured‚ or sprained something in your body before. And you had to take that dreadful trip to the ER after whatever crazy and or stupid thing you just did. Or it might even just been from you playing the sport you love. My favorite part of that trip is when they finally bring in the x-rays and you get to see the part of your body that should not look like it does in the picture. I’d love to share how some
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Osteogenesis Imperfecta: Brittle Bone Disease Sami Gizara Lakeland High School Honors Biology Block 6 March 10‚ 2013 Current Applications in Science Abstract (Summary and Background) Osteogenesis Imperfecta was a severe‚ congenital genetic disorder which can cause the human bones to be extremely delicate. This disease is caused by a mutation(whether it be deletion or duplication) in chromosome 17q21‚ 31-q22‚ 7q22.1‚ which are the chromosomes that help the body produce the proteins
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PH210 PHARMACY CLERKSHIP HOSPITAL PUTRAJAYA Case 5 Congestive Cardiac Failure Nephrotic Syndrome Community-Acquired pneumonia Siti Hasmah Bt Mohd Suffian (2006200606) CASE SUBJECT Name: MAM Gender: Male Age: 24 years old Race: Malay Weight: 138 kg BMI: 55 (morbidly obese) Height: 159cm DOA: 21st March 2010 SUBJECTIVE Chief complaint: • bilateral lower limb swelling for the past 2 weeks. • scrotal swelling for the past 3 days but noted on DOA had progressively
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