Name: Bill Marano Due Date: 4-1-13 Experiment Title: TLC Analysis of Analgesic Drugs Purpose: The purpose of this experiment is to identify the brand name of an unknown commercial analgesic product by TLC analysis. Unknown #1 solution was run against standard solutions of individual analgesics. The components of the unknown product were identified by comparing characteristic traits‚ such as Rf‚ fluorescence and iodine staining‚ to those exhibited by the standards. The name of the commercial product
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January 24‚ 2013 TLC Analysis of Analgesic Drugs Introduction: The purpose of this lab was to determine the composition of four different over-the-counter drugs (Anacin‚ Bufferin‚ Excedrin‚ and Tylenol). These compositions were determined by using the method of thin-layer chromatography (TLC) of the four over-the-counter drugs‚ which were then compared to four different components of drugs (acetaminophen‚ aspirin‚ caffeine‚ and salicylamide). Experiment Scheme1:
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Abstract: In this lab‚ the chemical components of Excedrin and Tylenol‚ two common‚ over-the-counter analgesic drugs‚ were determined by utilizing the technique of thin-layer chromatography‚ or TLC. The active ingredients of Excedrin were caffeine‚ acetaminophen‚ and aspirin with Rf values of 0.11‚ 0.38‚ and 0.61‚ respectively. The lone active ingredient of Tylenol was acetaminophen with an Rf value of 0.39. The elution sequence obtained in the experiment is as follows: ibuprofen (least polar)
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To: Wesley Clark From: Lizzie Heath Date: March 4‚ 2013 Subject: Thin-Layer Chromatographic Analysis of Drug Components (Experiment #15) The purpose of this experiment is to determine the components of an unknown drug and identify it as one of six (6) commercial drugs by using thin-layer chromatography. I added approximately a quarter of a tablet of acetaminophen‚ aspirin‚ caffeine‚ ibuprofen‚ salicylamide‚ and the unknown (#19) to separate test tubes containing 2.5mL of dichloromethane
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THIN LAYER CHROMATOGRAPHY ANALYSIS (TLC) COORDINATORS: ASSOC. PROF. DR. JAMALUDDIN BIN MOHD DAUD ABDUL AZIM ADNAN 1016741 INTRODUCTION TLC chromatography or thin layer chromatography is a type of planar chromatography. TLC is routinely used by researcher in the field of phyto-chemicals‚ biochemistry etc. to identify the components in a compound mixture like alkaloids‚ phospholipids‚ amino acids etc. It is a semi quantitative method of analysis and its sophisticated
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2a: Infrared Spectroscopy and Analgesic Drug Identification Abstract: To be able to understand how organic soluble compounds could be isolated from non-organic components‚ a chromatographic separation process was used. The objective of the analgesic drug identification is to isolate the organic compounds/ active ingredients in an unknown drug. The identity of the drug was determined through melting point‚ percent recover‚ and Rf values. The comparable data for acetaminophen from the manufacturer
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ingredient in an Analgesic Drug from extraction‚ filtration and melting point. Chm237 Abstract: Acetaminaphen was crushed then extracted for the active ingredient by mixing it with methanol. Then separated from the binders by centrifugation and a filtration technique using a Pasteur pipet packed with alumina. The remaining solvent was then evaporated to yield the solid analgesic(.2295g‚ 45.9% yield) which was collected by filtration and tested for the purity of the drug by the melting
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Sasha Thiel 09.10.2012 CH203 Lab Experiment 1: Isolation of the Active Ingredient in an Analgesic Drug Pre-Lab: A. Least accurate to most accurate 1. Beakers (5ml markings) 2. 10ml graduated cylinder (0.1 markings) 3. 5ml vials (0.1 and 0.3 markings) 4. 1ml plastic pipets (0.1 ml markings) 5. 1ml syringes (0.1 ml markings) 6. 1ml graduated volumetric pipets (0.01 ml markings) B. A 1ml graduated volumetric pipet is the best to use if you want 0.15 ml of reactant
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with the eluent that is lower in polarity. 2. TLC in today’s experiment stands for Thin Layer Chromatography. 3. From least polar to the most polar: Heptane-Toluene-Acetone-Methanol-Acetic acid ‚ ‚ ‚ ‚ 4. The Rf (Retardation factor) is the ratio of the distance that the compound/mixture traveled to the distance the solvent/mobile phase traveled. 5. From least Rf to the highest Rf: Benzoic acid – Benzaladehyde - n-Decane If the TLC were run with a more polar solvent‚ all the
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16 Application of TLC in the Isolation and Analysis of Flavonoids Marica Medi-Šari‚ Ivona Jasprica‚ c c Ana Mornar‚ and Željan Maleš CONTENTS Introduction ................................................................................................ 405 16.1.1 Chemistry‚ Biochemistry‚ and Medicinal Significance of the Flavonoids.......................................................................... 405 16.1.2 Brief Overview of Use of TLC in the Analysis of Flavonoids in Plants ........
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