with the higher dosage (Sikora‚ R.‚ Sohn‚ M.H.‚ Engelke‚ B. et al. 1998). Two placebo controlled trials‚ with a total of 190 patients‚ showed improved walking distance and decreased pain in patients with peripheral vascular disease. Schizophernia In a study fifty-four patients with chronic refractory schizophrenia‚ twenty-seven were treated with haloperidol plus Ginkgo biloba‚ and the rest received haloperidol plus placebo. Based on the observations it was concluded that Ginkgo biloba may enhance the
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the effectiveness of Homeopathy‚ to determine whether it has a physiological effect on the body past the placebo effect. I wanted to determine if homeopathy didn’t actually work did it still have a use in the NHS‚ as it may improve patient satisfaction and could improve their health? Is it ethical for Doctors to prescribe homeopathic remedies if they do not actually work that are purely placebos? What is the public and professional opinion on Homeopathy? Finally after finding all this evidence should
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Florian Koppelstatter reported an experiment in which he used functional magnetic resonance imaging(fMRI) to determine how coffee effects brain activity. Subjects were then given either a cup of strong coffee‚ containing 100 mg of caffeine‚ or a placebo drink. Twenty minutes later‚ all participants underwent fMRI scans while carrying out a memory and concentration test. The subjects who received the caffeinated coffee demonstrated increased activity in brain regions located in the frontal lobe
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stayed on the same dose for 1 year more‚ in a 1:1 proportion. Those previously receiving placebo either received daclizumab HYP 150 or 300 mg again in a 1:1 proportion during 1 year. In these patients‚ the relapse rate at the end of the study was reduced by 59% (p<0.001)‚ with no discrimination between the two different doses of the mAb. The number of new or enlarging T2 lesions was 8.0 after the first year on placebo and switching to daclizumab in the SELECTION trial justified a reduction of 74% in this
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ive placebos worked great because they triggered powerful hope and fear in their targets. And our present day civilization has many‚ many witch doctors. The medical industrial complex is a good example. Much of what the medical establishment does is hugely beneficial. Research‚ diagnostic tests‚ drugs‚ surgery‚ and trauma management have been wonderful blessings for mankind. But the medical industrial complex is also very big business. Researchers‚ medical staff‚ drug companies‚ and
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2015). A placebo test was done in 1997 where 262 patients were confirmed with a RPBV‚ half were given the Rapivab and half were given the placebo. Of the half given the Rapivab‚ 76% recovered in a time period one or two days sooner than those with the placebo‚ discounting the individual who suffered from disease complication (Hayden‚ et al.‚ 1997). The drug did not cause serious adverse reactions but did cause insomnia‚ constipation‚ diarrhoea‚ and high blood pressure (Cunha‚
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fluoxetine in the acute treatment of depression. The effects were determined by a randomized double blind control trial in which the control group were compared to the placebo group. The main findings of the article were that the control group given the SSRI fluoxetine showed greater improvements in terms of treatment of depression than the placebo group‚ and the SSRI showed more significant results as an anti-depressant than tricylic agents that were presented in previous studies mentioned in the article
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were 348 patients in the LUM (600mg/day)-IVA group‚ 344 patients in the LUM (400 mg every 12 hrs)-IVA group‚ and 362 patients in the placebo group who completed the study. This randomized study was stratified evenly according to several factors including age (< 0.001). Until the end of the study the rate of pulmonary exacerbations were continuously lower than the placebo group. Concomitantly‚ a reduced number of pulmonary exacerbations through the lumacaftor-ivacaftor groups also decreased the number
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answers to the question that whether it is ethical to implement a placebo-controlled trial for the purpose of testing whether the new drugs are efficient. Holding all other things constant‚ utilitarians might conclude that it is correct to conduct the placebo-controlled trial if the benefits outweigh the costs‚ while a deontologist would argue that it is unacceptable to apply placebo to a set of people instead of efficient drugs since placebo might be harmful to their health. Different from utilitarianism
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between treatment (typical anti-psychotics) and placebo groups‚ in that those in the placebo groups were more likely to relapse. This difference was found in every study reviewed‚ this therefore supports the effectiveness of the use of typical anti-psychotics drugs to treat schizophrenia as it shows‚ anti-psychotics had made a significant‚ persistent change to the secretion of dopamine in schizophrenic users. However Rose and Read (2004) argue that placebo studies are not a fair comparison of treatment
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