The Metabolic fate of ethyl O-[N-(p-carboxyphenyl)-carbamoyl] mycophenolate (CAM)‚ a new anticancer agent‚ in experimental animals. The pharmacokinetics of a new anti-tumor agent i.e. ethyl o- [N-(p- carboxy phenyl)- carbamoyl] Mycophenolate (CAM) was studied in mice by using 14 c-labeled CAM and also metabolic differences were studied in species like rats‚ mice‚ rabbits‚ guinea pigs & dogs. The
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Zoology‚ Geography etc. Professional subjects studied during the course include: Professional Practice Introduction to Pharmacy Pharmacognosy Pharmaceutics Pharmacy Calculations Pharmacology Biopharmaceutics Pharmacokinetics/Clinical Pharmacokinetics 1 Clinical Pharmacy and Therapeutics Forensic Pharmacy Pharmacy Administration Pharmaceutical Analysis Professional Practice This course allows the students to extend their knowledge in a practical environment
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purpose of the paper is to discuss Xanax also known as Alprazolam (generic version). This paper will go over the brief history and overview of what the prescription medication Xanax is and what it is used for. This paper will also discuss the Pharmacokinetics and Pharmacodynamics. Not only does Xanax affect people different it also is a highly addictive Benzodiazepine. A discussion on the adverse effects of Xanax will be discussed within the paper as well as side effects. In many cases‚ when one builds
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PCP/Angel Dust (Phencyclidine) Classification: hallucinogenic MW: 243.394 g/mol pKa: 8.29 Chemical Formula: C_17 H_25 N IUPAC name: 1-(1-phenylcyclohexyl)piperidine Description Phencyclidine also known as PCP‚ is a hallucinogenic which is normally used as an veterinary anesthetic. PCP is similar to another hallucinogenic drug‚ Ketamine‚ based on their structure and effects on the person. PCP causes a dissociative state by inhibiting NMDA receptors (N-methyl-D-aspartate). [1‚2‚3]PCP
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CHANTIX® (varenicline) Tablets DESCRIPTION CHANTIX® tablets contain the active ingredient‚ varenicline (as the tartrate salt)‚ which is a partial agonist selective for α4β2 nicotinic acetylcholine receptor subtypes. Varenicline‚ as the tartrate salt‚ is a powder which is a white to off-white to slightly yellow solid with the following chemical name: 7‚8‚9‚10-tetrahydro-6‚10-methano-6H-pyrazino[2‚3h][3]benzazepine‚ (2R‚3R)-2‚3-dihydroxybutanedioate (1:1). It is highly soluble in water. Varenicline
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integrating through definite integration. Finding the total AUC could be represented by the equation below: AUC= t= 0t= Cptdt Where Cptrepresents the Plasma concentration equation of each individual segment. When observing the general shape of any pharmacokinetic profile‚ it is evident that they all follow the shape and curve of an exponential function.This allows us to express Cptas: Cpt= Cp0e-kelt= DoseVe-kelt We can now substitute this equation into the previous equation to create an analytical equation
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and described nearly a thousand different pharmacological treatments…and is often referred to as the ‘father of pharmacology’” (Schanger & Lauer 2001). Pharmacology is generally split into two main branches‚ pharmacodynamics and pharmacokinetics (Lapensee 2012). Pharmacodynamics is the study of what a drug
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J. Ara b Neonatal Forum 2005; 2: 1-4 Drug Metabolism in the Neonate Imti Choonara Academic Division of Child Health‚ University of Nottingham‚ Clinical Sciences Wing The Medical School‚ Derbyshire Children ’s Hospital‚ UK _____________________________________________________________________________________________ Abstract The newborn infant has a reduced capacity for drug metab olism in comp arison with infants and children. This is more marked in the preterm neonate. Altered drug metabolism
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Jentadueto (linagliptin plus metformin hydrochloride) & Sklice (ivermectin) Lotion New Medications Approved by the FDA in 2012 Jentadueto (linagliptin plus metformin hydrochloride) In Boehringer Ingelheim (2012) Jentadueto combines two antipyperglycemic agents with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes mellitus: linagliptin‚ a dipeptidyl peptidase-4 (DPP-4)‚ and metformin‚ a member of the biguanide class.
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1. Ceftriaxone Sodium 1g IV Fig. 1.1 Ceftriaxone (Rocephin) It inhibits the cell wall synthesis promoting osmotic instability‚ usually bactericidal. It hinders or kills bacteria. Ceftriaxone sodium is a broad-spectrum bactericidal cephalosporin antibiotic. Ceftriaxone is active in vitro against a wide range of Gram-positive and Gram-negative organisms‚ which include β-lactamase producing strains. Ceftriaxone is indicated in the treatment of the following infections either before the infecting
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