Drug Metabolism Prof. Patrick Davis Basic Medicinal Chemical Principles PHR 143M Fall-08 Importance of Drug Metabolism • The basic premise: Lipophilic Drugs --> Hydrophilic Metabolites (Not Excreted) (Excreted) • Water soluble => increased renal excretion -anddecreased tubular re-absorption of lipophilics. Importance of Drug Metabolism CH 3 CH 2OH CHO COOH OH O C 2H 5 Δ1-THC PC=6000 - O C O O HO OH COO OH OH Excreted Form O C 2H 5
Premium Pharmacology Metabolism
2. Compare the development of lymphocytes with other formed elements. B lymphocytes develop in red bone marrow‚ T lymphocytes develop in red bone marrow and mature in the thymus; the other formed elements develop in red bone marrow 3. What is erythropoiesis? Which factors speed up and slow down erythropoiesis? Erythropoiesis is the process by which red blood cells (erythrocytes) are produced. If you lose a lot of blood‚ erythropoiesis will speed up; anemia can cause erythropoiesis to slow down
Premium Immune system Red blood cell White blood cell
(P1) Outline the functions of the main cell components Every individual possess billions of cells in their body but not only is the human body functional With cells but also contains tissues‚ organs and systems which is what the human body is made up of. The cell carries out vast numbers of chemical reactions which processes in order to make up the essence of life (Moonie N‚ Aldworth C‚ Billingham M & Talman H ‚2012). Cells are usually grouped together with other cells carrying out particular
Premium Cell Protein Organelle
Abstract here) GMOs Causing More Harm than Good A statement was issued by the U.S. Food and Drug Administration in the early 1990’s that advised consumers that there had been no danger associated with consuming foods containing Genetically Modified Organisms (GMOs) therefore no “safety” studies were necessary. The FDA furthermore made the ruling that the labeling of GMO foods was not mandatory in the year 2000. In 1992 a lawsuit against the BIOTECH community released 44‚000 secret internal memos into
Premium
1 SN2 Reaction‚ Ionic Liquid (Group – hood) Background Reading Solomons and Fryhle Chapter 6 (Substitution/Elimination Reactions) Techniques: Weights and Measures‚ Reflux‚ Liquid-Liquid Extraction‚ Distillation. Introduction The SN2 reaction is a bimolecular nucleophilic substitution reaction where the nucleophile (a molecule with a free pair of electrons) reacts with an alkyl halide and replaces the halogen (for more details see Solomons and Fryle‚ Chapter 6). The nucleophile approaches
Premium Distillation Solvent Laboratory glassware
LABORATORY REPORT RENAL PHYSIOLOGY INTRODUCTION: The kidneys‚ which maintain the purity and constancy of our internal fluids‚ are perfect examples of homeostatic organs. They regulate the chemical content the pH and osmotic pressure of the blood. Kidneys filter gallons of fluid from the bloodstream. They then process this filtrate‚ allowing wastes and excess ions to leave the body in urine while returning needed substances to the blood in just the right proportions. Factors that affect urine
Free Urine Kidney
This essay will outline the functions of the main cell components‚ these consist of the nucleus‚ nuclear membrane‚ mitochondria‚ lysosomes‚ Golgi apparatus‚ cell membrane‚ ribosomes‚ cytoplasm and endoplasmic reticulum both rough and smooth. Images: [3] Every human body has billions of microscopic units called cells. Cells carry out numerous of chemical reactions and processes that make up the essence of life. The structure of cells varies in size and shape and has different functions. There
Premium Protein Cell Cell nucleus
My Anatomy and Physiology of Love I am on a deep REM sleep And I dreamt of you my precious that I keep I was in the lab and I am dissecting something What?! Me myself? It’s me I’m killing??! No‚ my dear it isn’t I am just diagnosing myself About my feelings for my conscious health This heart of mine beating lub dub for you Hoping you’ll hear it by your auditory nerves too. When I first saw you my optic nerves were cursed By your.. orbicularis oculi and oris With your personality
Premium Marriage Anatomy Biology
Course Outline (Undergraduate): Course Title Systemic Physiology I Course Code LFS201 Faculty of Science‚ Health and Education Semester 1‚ 2011 DISABILITY AND LEARNING SUPPORT SERVICES The University offers a range of services and supports for students with a disability and it is important that these are negotiated early in the semester. Students who require alternative arrangements such as Special Exam Arrangements and assessment or study support should discuss their needs with the Disability
Premium Education Psychology Disability
Clint Casey Planarians I. Diet: Planarians are carnivorous and eat other smaller animals. They also eat detritus‚ diatoms‚ dead animals‚ and decaying organic matter. (1) II. Predators: Larger carnivores eat planarians. Some fish such as the Crossocheilus siamensis (Siamese Algae Eater) have been studied to remove planarians from fish tanks. (3) III. Range: Most planarians live in fresh-water bodies. They also live in all oceans‚ and in moist terrestrial habitats. (5) IV. Microhabitat:
Premium Reproduction Inch Fish