Sickle-Cell Anemia is an inherited‚ chronic blood disease in which the body produces abnormally shaped red blood cells. When the blood cells become crescent/sickle shaped‚ they are unable to deliver adequate amounts of oxygen to other cells. Also‚ these unusual “sickle” cells block blood pathways to the limbs and organs‚ limiting the amount of blood flowing throughout the body. It causes pain‚ organ damage‚ and anemia (low blood count). Unfortunately‚ however‚ when sufferers are born with this disease
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What is it? Sickle cell anemia is a type of blood disorder that can be inherited from parents. This is when red blood cells that are meant to carry oxygen around the body become deformed. Normal red blood cells are round and disc shaped‚ however‚ when they become sickle red blood cells‚ the deform and change shape into a crescent-like shape or sickle shape. The sickle cells have a shorter life-span than a healthy red blood cell and are not replaced as quickly as normal; this leads to a shortage
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Sickle Cell Anemia Pathophysiology: Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal crescent shape. The “sickling” occurs because of a mutation in the hemoglobin gene. Sickle cells are stiff and sticky. They tend to block blood flow in the blood vessels of the limbs and organs. Blocked blood flow can cause pain‚ serious infections‚ and organ damage. Life expectancy in people who have this disease is shortened. Anemia is a condition in
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SICKLE CELL ANEMIA Tina Thompson‚ Ashley Scott‚ Araceli Galindo‚ Roshanda Dixon‚ Kristen Wyatt‚ Kimberly Dennis What is Sickle Cell Anemia? Sickle cell anemia is a severe hemolytic anemia resulting in a sickle shaped hemoglobin molecule. It is an inherited disorder with some having sickle cell trait and some having sickle cell disease. The sickle hemoglobin gene is known as the HbS gene. It is found predominantly in people of African descent and occasionally in those of Mediterranean descent
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is that sickle cell anemia affects about 72‚000 Americans in the United States. Sickle cell anemia is an inherited disease in which the body is unable to produce normal hemoglobin‚ an iron-containing protein. Abnormal hemoglobin can morph cells that can become lodged in narrow blood vessels‚ blocking oxygen from reaching organs and tissues. The effects of sickle cell anemia are bouts of extreme pain‚ infectious‚ fever‚ jaundice‚ stroke‚ slow growth‚ organ‚ and failure. Sickle cell anemia hurts
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Sickle Cell Anemia Sickle cell anemia is an inherited blood disease. The word anemia is defined as meaning that the blood does not have the required number of red blood cells. These cells take on a crescent shape‚ which is where the disease takes its name from the abnormal sickle shapes of the cells. It is commonly found in people from Africa‚ the Mediterranean region‚ southern India and the Middle East. “This disease of the blood was first discovered in 1910 in a black college student from the
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OMATSEYE Everglades University Mr. Kirk Webster Sickle Cell Anemia Sickle cell anemia or also known as sickle cell disease is a hereditary genetic disease defined by the presence of odd shaped crescent-shaped red blood cells instead of the regular round disc like shape cells. Red blood cells transport oxygen from the lungs to various other organs and tissues with the help of a protein called hemoglobin. The main cause of sickle cell disease is when hemoglobin mutates into an abnormal type
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TREATMENT OPTIONS There is NO cure for sickle cell disease‚ although new stem cell research is promising. Bone marrow transplant is a potential cure‚ however finding a matched sibling donor is difficult. Therefore treatment is primarily focused on management of symptoms and prevention of pain episodes. Hydroxyurea (a chemotherapeutic medication) is the only recognized treatment option for the prevention of vaso-occlusive crisis in SCD. It is a prescribed drug for adult patients
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episodic sickle cell crisis such as staying adequately hydrated‚ limiting physical activities‚ blood transfusions and taking medication such as hydroxyurea. In Addition‚ one of the biggest issue with Sickle cell anemia is lack of funding which is due to the fact that it is not officially recognized as a health disparity topic by CDC. Another disparity is the fact that in terms of funding and treatment; SCD pales in comparison to other diseases. the funding disparities for research on sickle cell drugs
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‘How could natural selection increase the number of children born with sickle-cell disease in certain regions when these individuals are unlikely to survive and produce offspring?’ Darwin’s theory proposes that 3 conditions are a requisite for natural selection to occur. They are a struggle for existence of the offspring as they are competing for limited resources‚ variation within species which gives some individuals advantage over others hence better chance of survival and lastly inheritance
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