of Controlled Release 183 (2014) 87–93 Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Antibody–drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranostics João Conde a‚b‚⁎‚1‚ Chenchen Bao c‚ Daxiang Cui c‚ Pedro V. Baptista b‚ Furong Tian d‚⁎⁎ a Instituto de Nanociencia de Aragon (INA)‚ Universidad de Zaragoza‚ Zaragoza 50018‚ Spain CIGMH‚ Departamento de Ciências da Vida‚ Faculdade
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Carbohydrate Polymers 95 (2013) 530–539 Contents lists available at SciVerse ScienceDirect Carbohydrate Polymers journal homepage: www.elsevier.com/locate/carbpol In vivo evaluation of chitosan–PVP–titanium dioxide nanocomposite as wound dressing material D. Archana a ‚ Brijesh K. Singh a ‚ Joydeep Dutta b ‚ P.K. Dutta a‚∗ a b Department of Chemistry‚ Motilal Nehru National Institute of Technology‚ Allahabad 211004‚ India Department of Humanities and Applied Sciences‚ Institute
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Transfers in Contemplation of Death‚ Art. 728-731 ALEJANDRO V. GERALDEZ‚ 78 SCRA 245 (1977) FACTS: Petition for Review on Certiorari of the decisions of the CFI of Bulacan This is a case about donations inter vivos and mortis causa. The bone of contention is Lot No. 2502 of the Lolomboy Friar Lands Estate with an area of 5‚ 678 sq. meters‚ situated in Sta. Maria Bulacan. Sps. Gavino Diaz and Severa Mendoza executed a Deed of Donation in favor of their children‚ Olimpia‚ Angel‚ Andrea Diaz‚ and
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this period. The Graded Muscle Response to Increased Stimulus Intensity 3. From Activity 3‚ describe the effect of increasing the voltage. What happened to the force generated and why did this change occur? 4. How does this change occur in vivo? 5. In Activity 4‚ you looked at the effect of stimulating the muscle multiple times in a short period with complete
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Gene doping: the hype and the reality Genetic manipulation has produced some potential advantages to be able to alter the cells in animal models of human diseases‚ which may make disease as a thing of the past and help with the development of better pharmaceutical products in order to extend the human life spans‚ however‚ there are still major technological obstacles that require further research to ensure the methods and effects of genetic manipulation. The gene therapy products may not only be
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Session 28 Safety Pharmacology Studies for Human Pharmaceuticals This guidance was developed to help protect clinical trial participants and patients receiving marketed products from potential adverse effects of pharmaceuticals‚ while avoiding unnecessary use of animals and other resources. This guidance provides a definition‚ general principles‚ and recommendations for safety pharmacology studies. Pharmacology studies have been performed worldwide for many years as part of the nonclinical
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Obsessive Compulsive Disorder (OCD) is a disorder in which patients have intrusive thoughts that lead them to do repetitive behaviors to ease their anxiety. Treatment options for Obsessive Compulsive Disorder such as Cognitive Behavioral Therapy‚ medication‚ and Psychotherapy can help the person suffering by reducing the frequency of compulsive behaviors. Cognitive Behavioral Therapy‚ also known as CBT‚ is an effective way for treating Obsessive Compulsive Disorder. CBT is the training of a patient’s
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on bone formation in vivo and in vitro.129 The inhibitory effect of TNFα on osteoblast differentiation was mediated through Runx2 inhibition and was NF-kB dependent220. TNFα- and TNFR1- deficient mice showed increased basal bone mass in vivo and increased OB differentiation in vitro.220 Neil et al.7 showed that inhibition of NF-κB using S1627 NF-κB inhibitor increased osteoblast differentiation and bone formation through the up-regulation of osteoblast specific genes in vivo followed by an increased
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phobia practices relaxation while imagining scenes of the fear-producing stimulus (Miltenberger‚ 2012). And In vivo desensitization is similar to systematic desensitization‚ except that the client gradually approaches or is gradually exposed to the actual fear-producing stimulus (Miltenberger‚ 2012). On a simple statement systematic the person relax while imaginative the fear stimulus and on vivo the person is expose gradually to the fear. The advantage of systematic is cheaper on monetary prospect &
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factor on angiogenesis in vivo. Circulation 92 (1992) S365– S371. 15. Leung‚ D.W.‚ Cachianes‚ G.‚ Kuang‚ W.J.‚ Goeddel‚ D.V.‚ & Ferrara‚ N.‚ Vascular endothelial growth factor is a secreted angiogenic mitogen. Science‚ (1989) 1306– 1309. 16. Bongrazio‚ M.‚ Da Silva-Azevedo‚ L.‚ Bergmann‚ E.C.‚ Baum‚ O.‚ Hinz‚ B.‚ & Pries‚ A.R.‚ Shear stress modulates the expression of thrombospondin-1 and CD36 in endothelial cells in vitro and during shear stress-induced angiogenesis in vivo. International Journal Immunopathology
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