GLUCOSE -6- PHOSPHATE DEHYDROGENASE DEFICIENCY DISEASE Keith Portillo 23 March 2007 Abstract: Glucose-6-phospate dehydrogenase deficiency (G6PD)‚ an X-linked inherited disease‚ is due to the lack of glucose-6-phosphate dehydrogenase. This enzyme is present in red blood cells and its deficiency can lead to hemolytic anemia. Red blood cells carry oxygen and G6PD protects these cells from natural oxygen chemicals that may build up when you have a fever or take certain medications. If there
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MODIFICATION OF THE HUMAN X-LINKED G6PD GENE & INDUCTION OF MALARIA RESISTANT GENES VIA STEM CELLS Abstract Glucose-6-phosphate dehydrogenase‚ also known as G6PD deficiency is one of the commonly known enzymes deficiencies in the human body and metabolism. Because some G6PD patients present a form of allergy to the fava bean‚ G6PD is also referred to as favism. Scriver‚ C.R et al (1995). According to Scriver C.R et al (1995)
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particles move towards anode. The rate of movement is dependent on factors such as size and charges. This technique is useful in diagnosis. For example‚ in diagnosing myocardial infection‚ electrophoresis is used to separate isoenzymes of lactase dehydrogenase and creatine kinase. Electrophoresis can also be used to separate blood proteins for accurate diagnosis of protein impaired metabolism such as patient with abnormal haemoglobin. Apart from that‚ electrophoresis can also be used as a method to separate
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rash and swelling of the face‚ fingers‚ feet‚ or legs are other side effects. Some of the reported cause are methemoglobin reductase‚ methemoglobinemia and sulfhemoglobinemia‚. This drug is not good for a person who has glucose-6-phosphate dehydrogenase deficiency because this drug can cause hemolysis (destruction of red blood cells) due to oxidative stress. It can cause serious damage if taken for long term. Many physicians prefer it to it take with antibiotics because this drug doesn’t kill the
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hereby state that the research project entitled “Consanguinity and G6PD deficiency in Omani children: a community-based cross-sectional study.”‚ is entirely my own work and/or specifically acknowledged wherever adapted from other sources. The research was carried out under the supervision and guidance of Dr. Nasser Al-Nazwani. Sumaiah Farook Date : Introduction Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is a hereditary condition in which red blood cells break down when the body
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The deficiency is carried by the X chromosome which makes the deficiency more common in males. People with favism lack sufficient amounts of the enzyme called glucose-6-phosphate dehydrogenase‚ also known as G6PD (Dr.Moalem 74). Although G6PD is thought to be present in every cell‚ it is essential in red blood cells for sustaining cellular integrity
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cotyledons of faba bean seeds‚ are glucopyranosides. It has been shown that active derivatives of vicine and convicine‚ divicine and isouramil‚ cause a disease known as favism‚ haemolytic anemia‚ in humans with a genetic deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD) (Crépon et al. 2010). Based on the content of vicine-convicine‚ faba bean is distinguished into two types: high vicine-convicine cultivars and low vicine-convicine cultivars (Duc et al.
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What Are Nutritional Deficiencies? The recommended daily amount (RDA) of a nutrient is determined by how much the body needs to stay healthy. Nutrients can be obtained in a variety of ways—from eating a varied diet to taking vitamin supplements. A nutritional deficiency occurs when the body doesn’t absorb the necessary amount of a nutrient. Deficiencies can lead to a variety of health problems‚ such as problems of digestion‚ skin problems‚ stunted or defective bone growth‚ and even dementia. What
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Deficiency diseases: Deficiency diseases are diseases caused by a lack of a certain vitamin or food type‚ they do what it says on the label‚ they obstruct everyday life and make easy tasks hard‚ e.g. rickets stop people from walking. Deficiency Diseases are diseases caused in humans that are directly or indirectly caused by a lack of essential nutrients in the diet. Nutritional diseases are commonly associated with chronicmalnutrition. Additionally‚ conditions such as obesity from overeating can
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Vitamin A. Deficiency Author: Michael Alan Hall Institution: Brandman University Abstract Vitamin A deficiency is a horrible disease. It causes side effects such as night blindness‚ conjuctival xerosis‚ bilot spots‚ corneal xerosis‚ corneal scars and xerophthalmia. Unfortunately this disease mostly affects the poor. The disease is not as prevalent in this country as it is in other such as Africa and Asia. It becomes worse because the citizens
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