CHAPTER EIGHT 8 AN OVERVIEW OF GENE EXPRESSION HOW TRANSCRIPTIONAL SWITCHES WORK THE MOLECULAR MECHANISMS THAT CREATE SPECIALIZED CELL TYPES POST-TRANSCRIPTIONAL CONTROLS Control of Gene Expression An organism’s DNA encodes all of the RNA and protein molecules that are needed to make its cells. Yet a complete description of the DNA sequence of an organism—be it the few million nucleotides of a bacterium or the few billion nucleotides in each human cell—does not enable us to reconstruct the
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people’s genes? These are some of the ethical questions raised by Christians. They believe that humans exist in God’s world and have no right to change it (“Moral”). People also argue that the human genome was given to you from birth and that it was generated by God. If we begin changing genes then it brings us back to ‘“playing God’”. Although these are popular questions that are asked about gene therapy‚ the most popular one and simple one is the safety of gene therapy. Although gene therapy has
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Limited Genetics transmission: Acquisition of characteristics by inheritance. Each cell in body contains nucleus which contains DNA. DNA is organized into long strands called chromosomes. Chromosome is made up of smaller units of DNA that is genes. Genes carry information on biological development of the body. Set of Chromosomes number: 23 pairs of chromosomes for each species‚ 46 altogether. Half of the inherited chromes are from the mother and the other matching half are from the father.
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010 Chapter 10 Gene Technology Student: _________________________________________________________ 1. Trimming certain genes out of molecules of DNA requires the use of special: A. digestive enzymes B. restriction enzymes C. enzymes from peroxisomes D. microscopic scalpels 2. To seal the cut fragments of DNA together‚ an enzyme called __________ is used. A. amylase B. peptidase C. trypsin D. ligase
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How do we know we know what each individual gene does? One way to investigate the function of a gene is to just remove the gene and analyze what happens to the organism. Let’s say we have a gene of unknown function in the human genome‚ an unidentified gene. First‚ compare it to other genes to see what similar sequences they have‚ if they code some similar sequences they might code for similar functions. However‚ if the gene the unidentified gene codes for something different we have seen before this
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(base sequence of RNA): AUG GGA AAU CAU CGG UGA Translation (amino acid sequence): Met (Start) Gly Asp His Arg Stop Mutated gene sequence one: 3’-T A C G C T T T A G T A G C C A T T-5’ Transcription (base sequence of RNA): AUG CGA AAU CAU CGG UAA Translation (amino acid sequence): Met(Start) Arg Asp His Arg Stop Mutated gene sequence two: 3’-T A A C C T T T A C T A G G C A C T-5’ Transcription (base sequence of RNA): AUU GGA AAU GAU CCG UGA Translation
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genetic conditions. The current on-going research is in the field of gene therapy‚ an experimental technique that uses genes to treat and replace the defective genes of an affected person. Instead of treating disease symptoms‚ this has the potential to correct the underlying cause (1). Besides its high costs and ethical concerns (therapy involving germ line treatment)‚ this technique also poses a considerable amount of risk. Thus‚ gene therapy is currently only being tested on the diseases for which
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While gene therapy holds promise as a revolutionary approach to treating disease‚ ethical concerns over its use and ramifications have been expressed by scientists and lay people alike. For example‚ since much needs to be learned about how these genes actually work and their long-term effect‚ is it ethical to test these therapies on humans‚ where they could have a disastrous result? As with most clinical trials concerning new therapies‚ including many drugs‚ the patients participating in these studies
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Averi Bates 4th Should Gene Editing Be Performed on Human Embryos? Gene editing is the changing of the human genome through artificial means like CRISPR. It has several possible outcomes both positive and negative. Some possible positive outcomes would be the eradication of genetic diseases and the genetic enhancement of humanity becomes more genetically perfect beings‚ the negatives would include the creation of horrible defects that replace those eradicated diseases or the creation of designer
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W4Q1 Meiosis is the process by which cells divide and create living creatures. Without meiosis we cannot have the process of mitosis‚ which is the process by which cells of tissue are created for living creatures. When meiosis occurs 4 daughter cells are created‚ while only 2 are created in mitosis. With the creation of 2 daughter cells the new cells will be similar to the parent cell‚ but will have differences‚ as there more parent cells involved. When mitosis occurs the daughter cells will be
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