Canavan’s disease is one of the most common and fatal progressive cerebellar degenerative disorder affecting the white matter of the brain which is caused due to the enzyme aspartoacylase. 1 Aspartoacylase (ASPA gene) promotes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate which is the only brain enzyme that has been shown to effectively metabolize NAA. 2 NAA metabolism plays a major role in the formation of myelin lipids. Oligodendrocytes present in the brain
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Parkinson’s disease is a progressive‚ neurodegenerative disease meaning it will worsen over time. It primarily affects dopamine neuron cells in the substantia nigra area of the brain‚ which is in the midbrain region. When the dopamine neuronal cells fall to a certain threshold level‚ symptoms will appear. One symptom is shakiness in the arms or hands‚ which are involuntary muscle tremors. These are uncontrollable jerky movements‚ regardless of whether the individual is resting or moving around
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daunting journey. However‚ it is an even bigger feat to live with Parkinson’s disease. Parkinson’s disease is a progressive disease of the nervous system recognized as muscular rigidity‚ and slow‚ imprecise movement‚ mainly affecting middle-aged and elderly people. It is associated with deterioration of the basal ganglia of the brain and a lack of the neurotransmitter dopamine. To live your best life with this disease one must not succumb to the temptation to hide away in their home. Also‚ you may
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ROLE OF MRI IN ALZHEIMER’S DISEASE INTRODUCTION Alzheimer’s disease is the most common causes of dementia‚ responsible for 60-80% of all dementias 2‚ 7. The prevalence is strongly linked to age‚ with >1% of 60-64-year-old patients being diagnosed with the condition‚ compared to 20-40% of those over 85-90 years of age 2. It is multifaceted disease which results in progressive cognitive decline that ultimately leads to dementia. Amyloid plaques and neurofibrillary tangles are considered as diagnostic
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Epidemiology: Chickenpox (Varicella) Sheree Criner‚ RN Grand Canyon University NRS 427 V December 21‚ 2014 Epidemiology: Chickenpox (Varicella) As stated by to Centers for Disease Control (CDC) (CDC‚ 2013); chickenpox is a very contagious disease caused by the varicella-zoster virus (VZV). VZV causes a primary infection that is characterized by a rash with macules‚ papules‚ and then vesicles. Other symptoms include fever‚ lethargy‚ and pruritus. VZV then remains in the body on the sensory nerve
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Clinical Feature Parkinson’s disease is a progressive‚ neurodegenerative ailment that affects movement‚ muscle control and balance as well as several other functions. It is part of a group of disorders known asmotor systems disorders. Parkinson’s disease was titled for James Parkinson‚ a general practitioner in London during the 19th century who first designated the symptoms of the disease. Parkinson’s disease is the most common movement ailment and the second most common neurodegenerative disorder
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In the modern world disease was a huge thing in the 20th century. There were many diseases that affected many people all around the world.many of them suffered or even died from it. Disease were very serious in the 20th century. The top main disease were HIVs‚ Malaria‚ Tuberculosis‚ Influenza‚ and SARS. One of the disease that started in the 20th century was HIV in the 1980s. HIV stands for human immunodeficiency virus. HIV was discovered by Luc Antoine Montagnier‚ a French virologist and joint
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HCS/235 January 19‚ 2015 Marc Schnitzer Health Care Museum Vaccination – Disease Prevention Although primitive forms of vaccination date back to the ancient Chinese‚ the creation of the small pox vaccine by Jenner in 1796 put vaccination into the mainstream of our healthcare system. In 1954‚ Saulk created the polio vaccine and in 1955 it was approved by the FDA for disbursement in the U.S. eventually eradicating the disease in this country. Vaccinations save our health care system over 14 billion
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Kandi Banks Alzheimer’s Disease Alzheimer’s disease is a progressive brain disease and is the most common form of dementia‚ a general term used for memory loss and the decline in intellectual and physical abilities. It most commonly is diagnosed in the elderly although there are cases of the disease occurring in people of middle age. There is no known single cause for Alzheimer’s although scientists believe that it occurs due to the chemical and structural changes in the brain which gradually
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Our brains go through many changes as we age just like the rest of our bodies. Alzheimer Disease is a progressive loss of structure‚ function and death of neurons which gradually declines the cognitive abilities that affects multiple systems. AD affects the cerebral cortex which is the outer and main part responsible for memory‚ learning and reasoning‚ language resulting in destroying the qualities that forms an individual’s distinctive character. When compared‚ many fewer nerve cells and synapses
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