MINIREVIEW Folate Receptor-Mediated Drug Targeting: From Therapeutics to Diagnostics ANDREW R. HILGENBRINK‚ PHILIP S. LOW Department of Chemistry‚ Purdue University‚ West Lafayette‚ Indiana 47907 Received 25 May 2005; accepted 27 June 2005 Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jps.20457 ABSTRACT: Folate targeted drug delivery has emerged as an alternative therapy for the treatment and imaging of many cancers and inflammatory diseases. Due to its
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ENG3U1-01 7 May 2012 Comparison of Antagonists in Lord of the Flies and Shutter Island As a social human‚ it is impossible not to write a distasteful person off as an enemy. Every little thing they do seems to be laced with bad intentions. The novel Lord of the Flies written by William Golding‚ and the film Shutter Island directed by Martin Scorsese are both texts that contain antagonist characters with unique and similar qualities. An antagonistic character is usually written to be driven
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Table of contents 1.0 Introduction 2 2.0 New Product Development of SK-II 3 2.1 Strategy 3 2.2 Idea Generation 4 2.3 Screening 5 2.4 Concept development and testing 6 2.5 Business analysis 7 2.6 Product Development and Testing 8 2.7 Test Marketing 8 2.8 Commercial and launch 9 3.0 Critical Issue of SK-II 11 4.0 Conclusion 12 References: 13 1.0 Introduction The Procter & Gamble Company (P&G) boasts boatloads of brands. The world ’s top maker of household products
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Name: Course: Professor: Date: Vatican II In October 11‚ 1962‚ over 2500 catholic bishops assembled in Rome under the leadership and guidance of Pope John XXIII. Top catholic leaders felt that the church needed urgent and radical reforms so as to make the church relevant and engage it to the modern world. The assembly took four years to come up with a set of regulations that governed the relationships of the Roman Catholic Church and the modern world. The gathering documented and referred to the
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Ramses II Imagine Egypt‚ in its prime. During the 19th Dynasty‚ where chariots might be racing through the streets‚ constructions of our modern day wonders were in progress‚ and merchants and artisans were in the busy market place selling their ware. Pharaohs ruled the land‚ and were seen as gods. During this famous time period‚ Ramses the second was the third ruler‚ 1279 - 1212 B.C. He was to be said to be the pharaoh in Exodus. Ramses was born to Queen Tuy and Seti I. He gained the throne
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Unit One Assignment: Ashurnasirpal II I have entered into the palace of the great Ashurnasirpal II‚ and am approaching the throne room to await my meeting with the king. In front of me are two Lamassu figures that guard the entrance‚ Colossal statue of a winged lion from the North-West Palace of Ashurnasirpal II (Fig. 1). I am immediately in awe of the sheer size of this pair of sculptures‚ they each stand over ten feet tall‚ towering over individuals who would like to enter the throne room. The
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REVISION CHAPTER 1 (from Mid-Semester Exam Sem. II 09/10) 1 2 Given the function : y 2 sin 2x 3 a) Find the i) amplitude ii) period iii) phase shift. . b) Sketch the graph of the function over one period. [6] 2 Find the exact value of the expressions below. Rationalize the denominator where appropriate: a) cot 70 tan 650 csc( 250 ) sec( 110 ) 5 19 tan cos 6 6 4 23 cot sin 3 6 [5] b)
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Maus II‚ by Art Spiegelman‚ continues the treacherous story of a Jewish Holocaust survivor from first hand memories. Artie Spiegelman is the son of Vladek Spiegelman and he is a graphic cartoon artist. He visits his father every so often and while he is there he makes sure to ask him about his experiences in Nazi Germany during the 1940’s. Vladek Spiegelman does not enjoy recalling his horrific memories but he agrees to do so anyway. Vladek begins telling his story to his son in Maus I and continues
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Philip II‚ king of Spain and only son of the Holy Roman emperor Charles V‚ had everything in his favor to become the dominant power in Europe and probably the world at that time. Nonetheless‚ he did not succeed in doing so due to his poor leadership‚ incompetence‚ bad fortune and his inept financial understanding. As an ardent Catholic defender and due to his strong sense of duty and devotion to his empire‚ Philip focused on expanding the Spanish realm throughout Europe and promoting Catholic faith
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Richard II‚ by William Shakespeare‚ is a play about a King whom is a poor chose in spending his countries wealth‚ separated from his subjects‚ and makes unwise decisions for counsel. Richard II then begins to lease land to wealthy noblemen and takes the money from a deceased uncle to fund his lifestyle the commoners and other noblemen become outraged. In the play there are symbolisms to England as being like “Eden”; and the first symbolism and maybe one of the most significant ones is by John of
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