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The effects of drugs on the mitochondria

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The effects of drugs on the mitochondria
Drug Cards
Ramipril:
Functional class: Antihypertensive
Chemical class: ACE inhibitors

Action: ACE inhibitors reduce ACE. ACE converts angiostenin I to angiostenin II, which narrows heart vessels, which causes high BP. ACE inhibitors prevent ACE from converting angiostenin I to angiostenin II. This results in the dilation of blood vessel, which lowers BP.

Adverse effects: Hypotension, angina, headache, fatigue, proteinuria, , rash, sweating, cough.

Contraindications: breastfeeding children, hypersensitivity to ACE inhibitors
PREGNANCY (D) 2nd,3rd trimester.

Dosage: Adult: PO: 2.5mg/day then 2.5-20 mg/day divided bid or daily.

Pharmokinetics: half life: 1-2 hrs, onset 1-2, peak 3-6.

Nursing implications: check for allergies. check for hypotension. check for edema

Atorvastatin:

Drug Cards
Ramipril:
Functional class: Antihypertensive
Chemical class: ACE inhibitors

Action: ACE inhibitors reduce ACE. ACE converts angiostenin I to angiostenin II, which narrows heart vessels, which causes high BP. ACE inhibitors prevent ACE from converting angiostenin I to angiostenin II. This results in the dilation of blood vessel, which lowers BP.

Adverse effects: Hypotension, angina, headache, fatigue, proteinuria, , rash, sweating, cough.

Contraindications: breastfeeding children, hypersensitivity to ACE inhibitors
PREGNANCY (D) 2nd,3rd trimester.

Dosage: Adult: PO: 2.5mg/day then 2.5-20 mg/day divided bid or daily.

Pharmokinetics: half life: 1-2 hrs, onset 1-2, peak 3-6.

Nursing implications: check for allergies. check for hypotension. check for edema

Atorvastatin:Drug Cards
Ramipril:
Functional class: Antihypertensive
Chemical class: ACE inhibitors

Action: ACE inhibitors reduce ACE. ACE converts angiostenin I to angiostenin II, which narrows heart vessels, which causes high BP. ACE inhibitors prevent ACE from converting angiostenin I to angiostenin II. This results in the dilation of blood vessel, which lowers BP.

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