Synthesis of Aspirin
The Synthesis of Aspirin
Chemistry Standard Level Lab Report
Data Collection and Processing and Conclusion and Evaluation
Date: December 8th, 2011
Purpose:
The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product.
Hypothesis:
I hypothesize that salicylic acid will react with acetic anhydride to produce acetylsalicylic acid (aspirin) and acetic acid (vinegar).
Variables:
Independent and controlled variables: The amount of sulfuric acid used for catalysis and the amount of salicylic acid and acetic anhydride.
Dependent variables: Theoretical and actual yield of aspirin.
Constant variables: Two beakers filled with 200 mL of water for the boiling water bath, the cold water bath and the temperature of the boiling water bath and cold water bath.
Materials:
Safety goggles, Lab coat, protective rubber gloves, notebook for observations, pen or pencil, four trays, 3 grams of salicylic acid, 125 mL Erlenmeyer flask, 8 mL of acetic anhydride, 8 drops of concentrated (85%) phosphoric or sulfuric acid, five 10 mL graduated cylinders, 50 mL graduated cylinder, hot plate, stirring rod, two 400 mL beakers, one 250 mL beaker, ring stand, utility clamp, filter paper, funnel, stopwatch, balance, two pipettes, scoopula, 6 test tubes, test tube stand, 0.1 grams of salicylic acid, 0.1 grams of commercial aspirin, 0.1 of handmade aspirin, 2.0 mL of Iron (III) chloride and cold water bath.
Procedure:
All the materials needed to begin were collected and the goggles, gloves and lab coat were worn for safety purposes. All the observations of synthesis of aspirin were recorded in tables in a notebook.
Preliminary steps:
The hot plate was set up first. A 400 mL beaker was filled with 200 mL of water and placed on the hot plate to boil. 3 mL of cold water and 60 mL of water were measured and
Chemistry Standard Level Lab Report
Data Collection and Processing and Conclusion and Evaluation
Date: December 8th, 2011
Purpose:
The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product.
Hypothesis:
I hypothesize that salicylic acid will react with acetic anhydride to produce acetylsalicylic acid (aspirin) and acetic acid (vinegar).
Variables:
Independent and controlled variables: The amount of sulfuric acid used for catalysis and the amount of salicylic acid and acetic anhydride.
Dependent variables: Theoretical and actual yield of aspirin.
Constant variables: Two beakers filled with 200 mL of water for the boiling water bath, the cold water bath and the temperature of the boiling water bath and cold water bath.
Materials:
Safety goggles, Lab coat, protective rubber gloves, notebook for observations, pen or pencil, four trays, 3 grams of salicylic acid, 125 mL Erlenmeyer flask, 8 mL of acetic anhydride, 8 drops of concentrated (85%) phosphoric or sulfuric acid, five 10 mL graduated cylinders, 50 mL graduated cylinder, hot plate, stirring rod, two 400 mL beakers, one 250 mL beaker, ring stand, utility clamp, filter paper, funnel, stopwatch, balance, two pipettes, scoopula, 6 test tubes, test tube stand, 0.1 grams of salicylic acid, 0.1 grams of commercial aspirin, 0.1 of handmade aspirin, 2.0 mL of Iron (III) chloride and cold water bath.
Procedure:
All the materials needed to begin were collected and the goggles, gloves and lab coat were worn for safety purposes. All the observations of synthesis of aspirin were recorded in tables in a notebook.
Preliminary steps:
The hot plate was set up first. A 400 mL beaker was filled with 200 mL of water and placed on the hot plate to boil. 3 mL of cold water and 60 mL of water were measured and