Rna Primase

DNA primase is an enzyme involved in the copping of DNA and is a type of RNA polymerase. Primase speed up the synthesis of a short RNA (or DNA in some organisms [1]) a part called a primer complementary to a ssDNA template. Primase is of key importance in DNA replication because no known replicative DNA polymerases can begin the synthesis of a DNA strand without an initial RNA or DNA primer. After this elongation, the RNA piece is removed by a 5' to 3' exonuclease and refilled with DNA. primase uses a phosphotransfer domain for the transfer coordination of metals, which makes it distinct from other polymerases. The side subunits include a NH2 and COOH terminal made of alpha helixes and beta sheets. The NH2 terminal reacts with a zinc binding