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Recombinant DNA is used to insert a gene for production of a protein of interest
The production of heat and drought resistant crops can alleviate world hunger around the world.
Production of clotting factors can treat bleeding disorders such a Haemophilia which casues bleeding into the joints and can be life threatening.
Hepatitis B vaccines are made with the help of yeast cells
It is used for the production of insulin which is used for treating diabetes which we are now going to look at in more detail.
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Insulin is an endocrine hormone produced by the pancreas
It helps keep your blood sugars from getting too high (known as hyperglycemia) …show more content…
Tetracycline is added and any bacteria that don’t have the recombinant DNA will be killed off
This insulin can then be harvested and used by diabetics
So we have looked at an example of where bacteria is used to make recombinant DNA. So, what other biological materials can be used? Yeast, a member of Kingdom Fungi, is a eukaryote. Yeast is used to make Hep B vaccines. A part of the Hep B virus gene is inserted into yeast cells. This codes for Hepatitis B surface antigen (HBsAg). The yeast cells multiply and the antigen can then be harvested and purified.
Why do we need to make vaccines and treatments using recombinant DNA?
Well, before now, many vaccines were made using plasma derived. In 1983, HIV, the virus that causes AIDS was discovered. We know now that this is transmitted through blood, however, before this was known, plasma derived vaccines were administered not knowing what blood borne diseases the donor carried. This resulted in patients developing AIDS. This also happened with haemophilia treatment
To avoid this, scientists discovered a way to produce the vaccines without blood donations ie DNA