Prevention of Atheromatous Heart Disease

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Prevention Of Atheromatous Heart Disease

By O.P. Agarwal, M.D., F.I.C.A.
Angiology, Vol 36, Number 8, August 1985
Presented at the 31st Annual Meeting, American College of Angiology and 26th Annual Meeting,International College of Angiology, November 5, 1984.

Abstract

Five thousand patients of atheromatous heart disease, presented as angina pectoris, were studied over a period of five years. After adding the “Husk of Isabgol” and “Aloe vera” (an indigenous plant known as ghee-guar-ka-paththa) to the diet, a marked reduction in total serum cholesterol, serum triglycerides, fasting and post parandial blood sugar level in diabetic patients, total lipids and also increase in HDL were noted. Simultaneously the clinical profile of these patients showed reduction in the frequency of anginal attacks and gradually, the drugs, like verapamil, nifedipine, beta-blockers and nitrates, were tapered. The patients, most benefitted, were diabetics (without adding any antidiabetic drug). The exact mechanism of the action of the above two substances is not known, but it appears, that probably they act by their high fibre contents. Both these substances need further evaluation. The most interesting aspect of the study was that no untoward side effect was noted and all the five thousand patients are surviving till date. Introduction

Incidence of atheromatous heart disease is increasing day by day. The factors commonly responsible for atherosclerotic heart disease are diabetes mellitus, hypertension, smoking, family tendency in the form of hyperlipidemias, gout, excessive intake of saturated fatty acids, obesity, lack of exercise, etc. For the first time, an Indian plant known as Aloe vera belonging to the Liliacee family along with the Husk of Isabgol, was tried on five thousand patients who had proved ischaemic heart disease due to atherosclerosis and the above two herbal medicines proved to be very effective when mixed with wheat flour paste before preparing the bread. This plant; Aloe vera, is used in Indian medicine as a tonic, purgative, aphrodisiac, antihelminthic, in various opthalmological disorders, enlargement of spleen, various forms of hepatitis, vomiting, fever due to bronchitis, erysipelas, skin disorders, asthma, leprosy, jaundice, strangury, as a carminative, various musculoskeletal disorders, menstrual suppression and various other nonspecific disorders.

Table I

Sex
Total
Patients
Age
Group
No. Of
Patients
Diabetic
Patients
Family
History Of
Diabetics
Total
Hyper- tensives
Mild
Moderate
M
3489
35-40
869
612
408
115
65
50
M
41-50
1050
823
639
325
201
124
M
51-65
1570
989
805
467
301
166
Non- Diabetic Patients
1065
589
381
208
F
1511
35-40
231
85
60
25
15
10
F
41-50
589
207
189
67
49
18
F
51-65
691
451
371
210
108
102
Non- Diabetic Patients
768
353
240
113
5000
5000
3167
2472
2151
1360
791
Table II

Age Group
No. Of
Patients
Anterior Wall
Ischaemia
Inferior Wall
Ischaemia
Male Diabetics
35-41
612
398
214
41-50
823
526
297
51-65
989
605
384
Male
Non-Diabetics
1065
424
641
Female Diabetics
35-40
85
31
54
41-50
207
96
111
51-65
451
302
149
Female
Non-Diabetics
768
438
330
5000
2820
2180
Table III
Fasting Blood Sugar (Normal 60-110 Mgm%)
Sex
Age
Group
No. Of
Patients
111-125
Mgm%
126-150
Mgm%
Males
35-40
612
398
214
41-50
823
564
259
51-65
989
598
391
Females
35-40
85
48
37
41-50
207
140
67
51-65
451
299
152
3167
2047
1120

Post Parendial Blood Sugar (Normal 100-160 Mgm%)
Sex
Age
Group
No. Of
Patients
161-250
Mgm%
251-400
Mgm%
Males
35-40
612
405
207
41-50
823
530
293
51-65
989
611
378
Females
35-40
85
42
43
41-50
207
131
76
51-65
451
305
146
3167
2024
1143
Table IV
Total Serum Cholesterol (Normal 125-285 Mgm%)
Sex
Age
Group
No. Of
Patients
286-350
Mgm%
351-425
Mgm%...
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