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  • Topic: Thyroid, Thyroid-stimulating hormone, Hypothyroidism
  • Pages : 7 (2462 words )
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  • Published : April 28, 2013
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Exercise 4: Endocrine System Physiology: Activity 1: Metabolism and Thyroid Hormone Lab Report Pre-lab Quiz Results You scored 33% by answering 2 out of 6 questions correctly. 1. Which of the following statements about metabolism is false? You correctly answered: d. All of the energy from metabolism is ultimately stored in the chemical bonds of ATP. 2. Thyroxine is Your answer : b. secreted by the thyrotropin gland, located in the neck.. Correct answer: c. the most important hormone for maintaining the metabolic rate and body temperature. 3. Thyroid-stimulating hormone (TSH) is Your answer : c. secreted by the posterior pituitary. Correct answer: b. produced in the pituitary gland. 4. An injection of TSH to an otherwise normal animal will cause which of the following? You correctly answered: d. goiter development 5. Thyrotropin-releasing hormone (TRH) is Your answer : c. held at a low plasma concentration by low levels of TSH. Correct answer: a. secreted by the hypothalamus. 6. Which of the following statements is true? Your answer : a. TRH travels from the hypothalamus to the thyroid gland via the hypothalamic-thyroid portal system. Correct answer: b. The hypothalamus primarily secretes tropic hormones that stimulate the secretion of other hormones.

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Experiment Results Predict Question: Predict Question 1: Make a prediction about the basal metabolic rate (BMR) of the remaining rats compared with the BMR of the normal rat you just measured. Your answer : c. The BMR of both remaining rats will be lower than the normal rat's BMR. Predict Question 2: What do you think will happen after you inject thyroxine into the three rats? Your answer : a. The normal rat will become hyperthyroidic and develop a goiter. Predict Question 3: What do you think will happen after you inject TSH into the three rats? Your answer : a. The normal rat will become hyperthyroidic and develop a goiter. Predict Question 4: Propylthiouracil (PTU) is a drug that inhibits the production of thyroxine by blocking the attachment of iodine to tyrosine residues in the follicle cells of the thyroid gland (iodinated tyrosines are linked together to form thyroxine). What do you think will happen after you inject PTU into the three rats? Your answer : c. The hypophysectomized rat will become hypothyroidic and develop a goiter. Stop & Think Questions: 1h. Calculate the oxygen consumption per hour for this rat using the following equation. ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour Enter the oxygen consumption per hour in the field below and then click Submit to display your results in the grid. You answered: 432 ml O2/hr 1i. Now that you have calculated the oxygen consumption per hour for this rat, you can calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the weight data from grams to kilograms to use this equation). Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr Enter the metabolic rate in the field below and then click Submit to display your results in the grid. You answered: 1721 ml O2/kg/hr 2h. Calculate the oxygen consumption per hour for this rat using the following equation. ml O2 consumed/1 minute x 60 minutes/hour = ml O2/hour Enter the oxygen consumption per hour in the field below and then click Submit to display your results in the grid. You answered: 378 ml O2/hr 2i. Now that you have calculated the oxygen consumption per hour for this rat, you can calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the weight data from grams to kilograms to use this equation). Metabolic rate = (ml O2/hr)/(weight in kg) = ml O2/kg/hr Enter the metabolic rate in the field below and then click Submit to display your results in the grid.

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You answered: 1542 ml O2/kg/hr 3h. Calculate the oxygen consumption per hour for this rat using the following equation. ml O2 consumed/1...
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