Preview

Parkinson's Research Paper: Why Men Are More Prevalent to the Disease

Powerful Essays
Open Document
Open Document
5647 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Parkinson's Research Paper: Why Men Are More Prevalent to the Disease
THE CAUSES OF PARKINSON’S DISEASE
AND WHY
IT AFFECTS PRODOMINANTLY THE MALE SEX

BY LEANNE JONES

Preceding Degree: BSc Adult (General) Nursing: 2011-2014
Previous Course: Access to Health & Nursing: 2010-2011

Secondary Research Report Presented as Partial Fulfillment to Attain Access to Health & Nursing

Faculty of Health and Nursing at South Essex College

ABSTRACT

Before examining the possible reasons why there appears to be an overwhelming prevalence of PD (Parkinson Disease) in men more than there is in women, it is imperative to this report that one firstly considers the general medical consensus of what the underlining causes of the condition are.

There are a variety of conditions that also affect the central nervous system, which at first glance may appear to be PD; presenting with similar symptoms. The primary cause of symptoms in PD sufferers is due to the reduced levels of Dopamine produced, which acts as a chemical messenger in the brain. The symptoms of PD include a sluggishness of movement, a certain rigidity and tremors, also statistically speaking in 1991 there was, on average, 1 in every 750 people diagnosed with PD.

Many authors recognise that men are almost twice as likely to develop PD as their female counterparts. Therefore the following explores the causes of Parkinson’s disease in order to investigate the possible reasons as to why men are more likely to be affected with condition than women.

-i-
-i-

ATTESTATION

I understand the nature of plagiarism, and am aware of the University’s policy on this project. I therefore certify that this report is based on secondary research material analysed by me during my project. The two main secondary sources are as follows:

The Michael J. Fox Foundation for Parkinson 's Research (December 21st 2006), Study Suggests Association between High Body Mass Index and Increased Parkinson 's Risk, Reuters Health. Accessed online:



Bibliography: * Allison Gandey (2009), Hormones Appear to Protect Women from Parkinson’s, Medscape Nurses LLC. Accessed online: www.medscape.com/viewarticle/590488 Date accessed: 10/01/2011 Boelen. M (2009), Health Professional’s Guide to the Physical Management of Parkinson’s Disease, Champaign, USA: Human Kinetics Brady. K, Back. S & Greenfield. S (2009), Women and Addiction: A Comprehensive Handbook, New York: The Guilford Press Corpus Striatum, Inset Image of fig.1, available at: http://www.thefullwiki.org/Striatum, accessed on: 20.01.11 D’Cruz, H & Jones, M (2002), Social Work Research: Ethical and Political Contexts, London: SAGE Publications. DeLong MR (1990), Primate Models of Movement Disorder of Basal Ganglia Origin, Trends Neurosci, Vol.13, No.7, p.281-5 Demirdamar. R (1998), Dopamine Receptor Subtypes: From Basic Science to Clinical Application, Netherlands: IOS Press Dr Fitzpatrick. J, & Wallace. M (2006), Encyclopedia of Nursing Research, Second Edition, New York: Springer Publishing Company, Inc. Freberg. L (2006), Discovering Biological Psychology, Second Edition, Belmont, USA: WADSWORTH, CENGAGE Learning Kaplan. P (2006), Neurological Disease in Women, Second Edition, New York: Demos Medical Publishing Inc. Oxtoby. M & Williams (1995), Parkinson 's at Your Fingertips: The Comprehensive Parkinson 's Reference Book for the Year 2000, London: Class Publishing Plumb Polit. D, & Beck. T (2004), Nursing Research: Principles and Methods, Seventh Edition, Philadelphia: Lippcott Williams & Wilkins Robson, C (2002), Real World Research, Second Edition, Oxford: Blacwell Publishing. Stommel. M, & Wills. C (2004), Clinical Research: Concepts and Principles for Advanced Practice Nurses, Philadelphia: Lippcott Williams & Wilkins Taylor

You May Also Find These Documents Helpful

  • Better Essays

    D1 receptors signal through G proteins to activate adenylate cyclase, causing cAMP formation and activation of PKA. D2-type receptors block this signaling by inhibiting adenylate cyclase. Parkinson’s disease can occur through both genetic mutation and exposure to environmental and neurotoxins. Recessively inherited mutations in Parkinson’s, DJ-1, and PINK1 cause mitochondrial dysfunction and accumulation of ROS, whereas dominantly inherited missense mutations in LRRK2 may affect protein degradation pathways, leading to protein aggregation and accumulation of Lewy bodies.…

    • 1182 Words
    • 5 Pages
    Better Essays
  • Good Essays

    In the movie Awakenings, a psychiatrist takes an interest in the patients that are in a statue-esque state. After much research and experimentation, he concludes that the patients were misdiagnosed, and actually have a severe case of Parkinson's disease. Parkinson's disease is a progressive nervous disease associated with the destruction of brain cells that produce dopamine and characterized by muscular tremor, slowing of movement, partial facial paralysis, peculiarity of gait and posture, and weakness. His experimental treatment included the new drug Dopamine, which is an antagonist in the brain, blocks the transmissions, and thereby limiting it, and increases Copamine in the synaptic gap.…

    • 385 Words
    • 2 Pages
    Good Essays
  • Better Essays

    "Caffeine may ease Parkinson 's symptoms." Obesity, Fitness & Wellness Week 18 Aug. 2012: 158. Academic OneFile. Web. 10 Apr. 2013.…

    • 1193 Words
    • 5 Pages
    Better Essays
  • Satisfactory Essays

    Physiological disorder

    • 378 Words
    • 2 Pages

    As a significant number of elderly patients with early Parkinson's disease symptoms assume that their traits may form part of normal aging and do not seek medical help, obtaining accurate statistics is probably impossible. There are also several different conditions which sometimes have comparable signs and symptoms to Parkinson's, such as drug-induced Parkinsonism, head trauma, encephalitis, stroke, Lewy body dementia, corticobasal degeneration, multiple system atrophy, and progressive supranuclear pasly`.…

    • 378 Words
    • 2 Pages
    Satisfactory Essays
  • Better Essays

    Parkinson’s is a chronic and slowly progressive disease. The symptoms continue and worsen over a period of years and the progression varies with each individual. Movement symptoms vary from person to person as well as the rate at which they progress. Some of the symptoms are more bothersome at different times of the day depending on what the person normally does during the day. The major symptoms of Parkinson’s include muscle stiffness or rigidity; tremors; bradykinesia, or the slowing down of movement and the gradual loss of spontaneous movement; changes in walking pattern and posture; changes in speech and handwriting; and loss of balance and increased falls.…

    • 1534 Words
    • 5 Pages
    Better Essays
  • Powerful Essays

    Nursing research.

    • 5090 Words
    • 16 Pages

    Dempsey, P.A. and Dempsey, A.D. (1996). Nursing Research: Text and workbook. 4th Edition. USA: Little, Brown & Co.…

    • 5090 Words
    • 16 Pages
    Powerful Essays
  • Powerful Essays

    Parkinson’s disease (PD) is a movement disorder characterized by tremor, rigidity, slowness of movement, and postural imbalance.…

    • 2822 Words
    • 12 Pages
    Powerful Essays
  • Good Essays

    Cited: M.D. Marjama-Lyons, J., & Shomon, M., (2003). What Your Doctor May Not Tell You About: Parkinson’s Disease, A Holistic Program for Optimal Wellness. New York, NY: Warner Books, Inc.…

    • 622 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Before 1817 Parkinson’s disease was called “Shaking Palsy.” James Parkinson wrote a medical essay on the disease entitled “An Essay on the Shaking Palsy.” However, 60 years after, Jean Martin Charcot (1825-1893), a French neurologist, discovered the importance of Parkinson’s essay and renamed the disease after Parkinson’s (Goetz 1).…

    • 1230 Words
    • 5 Pages
    Good Essays
  • Better Essays

    Parkinson's Disease

    • 1034 Words
    • 5 Pages

    Just imagine: your muscles going stiff, tremors running through your limbs constantly and the inability to smile and laugh with your grandchildren. This torment is the everyday experiences of a Parkinson's disease sufferer. Parkinson's disease is a growing concern in our nation, and though we know what the symptoms are, we do not know for sure what causes it, or even how to cure it. Throughout this paper, the definition will be described as well as the symptoms and treatment options.…

    • 1034 Words
    • 5 Pages
    Better Essays
  • Good Essays

    When a patient has lost nearly 80% of their dopamine cells, these symptoms being to appear. It is currently unknown why dopamine-producing cells deteriorate, but many theories lead to genetic, environmental, and age-related factors. Genetics factors cause of Parkinson’s disease through a mutation in the genes responsible for dopamine and other vital proteins. Environmental factors are thought to be associated with Parkinson’s in that exposure to certain toxins such as pesticides can play a significant role in the abnormal levels of dopamine produced. Age is also a definitive factor of the disease, because people under the age of 60 are rarely diagnosed (Triarhou,…

    • 911 Words
    • 4 Pages
    Good Essays
  • Good Essays

    One of the principal theories suggests the importance of oxidative stress as possible source of dopamine deficiency in Parkinson’s disease. The body’s immune cells can hunt free radicals, but if the immune system isn’t working optimally, free radicals can increase. The effects of free radicals can be reversed by nutrients known as antioxidants, such as vitamins C and E. These nutrients are able to give up parts of their cells, which then companion with the free radical and neutralize its damaging capacity. In case of Parkinson’s disease, scientists are trying to recognize aspects that cause oxidative stress on dopamine brain cells. When dopamine is broken down, it is processed into several different molecules, including peroxides, which react…

    • 211 Words
    • 1 Page
    Good Essays
  • Good Essays

    Parkinson's Disease is a disorder of the central nervous system. The disease is progressive, meaning that it gets worse as time goes on. People with Parkinson's disease may experience arthiritis, sporadic movements, poor posture and commonly shaking. Shaking usually occurs in the hands asymmetrically. Over 1 million Americans are affected by this disease today. 480 new cases are diagnosed each year. It was first recorded and researched by Dr. James…

    • 338 Words
    • 2 Pages
    Good Essays
  • Good Essays

    Parkinsonism Essay

    • 835 Words
    • 4 Pages

    In female patients, a varying degree of protection is observed, which is provided by the expression of the FMR1 gene from the normal X chromosome in a fraction of cells. This phenomenon usually results in less progressive, milder neurological symptoms in females than in males…

    • 835 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Parkinson's Disease

    • 793 Words
    • 4 Pages

    In the ancient Indian medical system of Ayurveda it is known as Kampavata and in Western medical literature it was described as “shaking palsy.” However, it was not until 1817 that a doctor named James Parkinson wrote an informative medical essay on the disease. It was called "An Essay on the Shaking Palsy". The writing was based on six cases he observed and its main purpose was to serve as motivation for other doctors and scientists to continue studying the disease and further the research in it. This established Parkinson's disease as a recognized medical condition. It wasn’t until about 60 years after it was published when a French neurologist, Jean Charcot, truly recognized the importance of Parkinson's work and named the disease after…

    • 793 Words
    • 4 Pages
    Good Essays