Oxycodone Research Paper

Oxycodone has various side effects including euphoria, dysphoria, lightheadedness, dizziness, anorexia, nausea, vomiting, jaundice, shortness of breath, pruitius, skin rash, bradycardia, unusual bleeding or bruising, dysuria, frequency of urination, and urinary retention (Wilson, Shannon, Shields 2016). The most common side effects are sedation and constipation (Wilson, Shannon, Shields 2016). Oxycodone can have life-threatening side effects such as respiratory depression and hepatoxicity, which is seen if oxycodone is combined with acetaminophen (Wilson, Shannon, Shields 2016). Oxycodone can interact with alcohol and St. John’s wort to increase sedation (Wilson, Shannon, Shields 2016) and “use of enzyme inducers such as rifampicin, St John’s wort and carbamazepine should be avoided because of the risk of subtherapeutic concentrations of oxycodone” (Söderberg Löfdal, Andersson, Gustafsson 2013). Onset of oxycodone can occur within 10 to 15 minutes and reaches a peak level of effect around 30 to 60 minutes with a duration of 4 to 5 hours but some doses may be prescribed for every 6 hours because the half-life of the drug can be from 3 to 5 hours which means that half of the dose is metabolized or broken down in your body within 3 to 5 hours (Wilson, Shannon,
If you have a history or currently dealing with alcoholism, renal or hepatic disease, viral infection, Addison’s disease, cardiac arrhythmia, chronic ulcerative colitis, history of drug abuse or dependency, gallbladder disease, acute abdominal conditions, head injury, intracranial lesions, hypothryroidism, respiratory disease, urethral stricture, peptic ulcer, or if you are pregnant or could be than you should talk to your doctor.[1] If you have any questions at any time, you can feel free to call the office and we will be happy to find you