Literature Review

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Literature Review:
Ghani et al (2008) conducted a research on the 2006 epidemic of dengue virus at a tertiary care centre in Sindh. The basic reason behind conducting research was to investigate the outcome of a selected group of patients who were either alleged or had been confirmed to be infected with the dengue virus and were being provided treatment at Liaquat Univesity Hospital in Hyderabad. The methodology that was used in this research was that 116 patients were kept under observation as they were being treated for the dengue infection. All relevant tests pertaining to finding out whether a person has dengue were conducted. These tests were like investigating the platelet count of the patient for thrombocytopenia, symptoms recognition like myalgia, high febrility, purpura and dengue antibody recognition etc. The clinical information conducted was also supported with other data gathering such as demographics and the data analysis was done on the SPSS 10.0 software. The findings that were registered indicated that out of 116 patients, only 52 patients had the dengue infection. Almost all of the confirmed cases had indications of thrombocytopenia and leucopenia which are key factors in determining the dengue virus. The mortality rate in this case was that of three deaths. Khan et al (2010) researched on a similar topic as done by Ghani et al (2008) and it relates to the incidence of dengue fever in a tertiary care hospital. The setup in which the research was conducted matched that of Ghani et al (2008) i.e. the sample was selected at Liaquat University Hospital in Hyderabad. The research was also descriptive in nature as it was meant to find out the number of patients who actually had dengue as they had initially been reported with dengue related symptoms but had not been proven positive as yet. The methodology in this regard was that patients and those also who were adults and had been reported with acute fever were checked for dengue fever. The methodology in this regard is different as it is looking into both dengue hemorrhagic and dengue shock syndrome which are varying grades of dengue infection. The procedure for investigating the symptoms was the same as in the case of Ghani et al (2008) in which clinical tests were conducted such as tourniquet test, hematological examination etc. The conclusion was that out of a total of 50 patients, only 20 were confirmed to be suffering from dengue fever out of which only 2 were listed as suffering from dengue hemorrhagic fever; no mortality rate was noticed.

Ayyub et al (2006) research is similar to the two that have been discussed before except that this time the setting is not of Pakistan and in fact has been done in a public hospital in Jeddah, Saudi Arabia. This particular research aims to target the clinical, laboratory and demographic profile of all the patients that have been confirmed with either dengue fever or dengue hemorrhagic fever and the hospital setting in this regard is King Abdulaziz Hospital & Oncology Center in Jeddah. The methodology followed in this regard was of similar nature to the previously mentioned researches. In this one a sample of 80 patients were considered. All of these patients had been admitted in the timeline of May 2004 till April 2005 and the patients’ symptoms were suspected to be that of either dengue fever or dengue hemorrhagic fever. Statistical profiling was done in which the factors that were considered were age, gender, monthly distribution, ethnicity clinical and laboratory profiles. The accumulated data was then analyzed using SPSS version 7.5 software. The findings indicated that out of 80 patients, only 39 patients were confirmed to have the dengue virus and the male to female ratio was 3.3:1. The duration of hospitalization was between 4 to 23 days thus making an average of 7.3 days. Eventually all patients showed signs of improvement and were completely treated towards the end of the period. Rahman et al...
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