Klinefelter syndrome research
KLINEFELTER SYNDROME RESEARCH 1
Klinefelter Syndrome Research
Duyen Le
Ap Biology
KLINEFELTER SYNDROME RESEARCH 2
Abstract
Klinefelter syndrome is the most common genetic disorder that affects males. The affected male has an extra copy of X chromosome, which means he has 47 chromosomes (XXY). The effects of Klinefelter syndrome vary by age; the patients with Klinefelter syndrome usually have weak muscles, slow motor development, small penis and testicles, enlarged breast tissue, attention problem, difficulty expressing feelings and socializing, taller than their peers etc. To determine whether you or your son has this disease, your doctor will likely examine your (your son) genital area and proceed some tests such as hormone testing, chromosome analysis. This disorder is not inherited because it occurs as a result of a random error in gamete production process. Klinefelter syndrome often isn’t diagnosed until adulthood; however, there are many treatments that can help the patients minimize problems such as testosterone replacement therapy, breast tissue removal, educational support…
KLINEFELTER SYNDROME RESEARCH 3
In 1942, Dr Harry and his fellows at Massachusetts General Hospital in Boston published a report about 9 men, who had enlarged breast tissue, sparse facial and body hair, small testes and unable to produce sperm. By the late 1950s, researchers discovered that men with those symptoms had an extra copy of X chromosome, and that means the chromosomal arrangement is XXY instead of XY as usual. In the early 1970s, researchers around the world sought to identify males having an extra chromosome. The result is 1 in 500 to 1000 newborn males have the XXY chromosome arrangement. Klinefelter disorder is a genetic condition but it is not inherited from parents. It usually happens randomly during meiosis; specifically chromosomes can’t
Klinefelter Syndrome Research
Duyen Le
Ap Biology
KLINEFELTER SYNDROME RESEARCH 2
Abstract
Klinefelter syndrome is the most common genetic disorder that affects males. The affected male has an extra copy of X chromosome, which means he has 47 chromosomes (XXY). The effects of Klinefelter syndrome vary by age; the patients with Klinefelter syndrome usually have weak muscles, slow motor development, small penis and testicles, enlarged breast tissue, attention problem, difficulty expressing feelings and socializing, taller than their peers etc. To determine whether you or your son has this disease, your doctor will likely examine your (your son) genital area and proceed some tests such as hormone testing, chromosome analysis. This disorder is not inherited because it occurs as a result of a random error in gamete production process. Klinefelter syndrome often isn’t diagnosed until adulthood; however, there are many treatments that can help the patients minimize problems such as testosterone replacement therapy, breast tissue removal, educational support…
KLINEFELTER SYNDROME RESEARCH 3
In 1942, Dr Harry and his fellows at Massachusetts General Hospital in Boston published a report about 9 men, who had enlarged breast tissue, sparse facial and body hair, small testes and unable to produce sperm. By the late 1950s, researchers discovered that men with those symptoms had an extra copy of X chromosome, and that means the chromosomal arrangement is XXY instead of XY as usual. In the early 1970s, researchers around the world sought to identify males having an extra chromosome. The result is 1 in 500 to 1000 newborn males have the XXY chromosome arrangement. Klinefelter disorder is a genetic condition but it is not inherited from parents. It usually happens randomly during meiosis; specifically chromosomes can’t
References: Diseases and Conditions Klinefelter Syndrome. In (2013), S. Mayo Clinic (Ed.), Mayo Foundation for Medical Education and Research… http://www.mayoclinic.org/diseases-conditions/klinefelter-syndrome/basics/definition/CON-20033637?p=1 Dr Kenny, T. (2013). Health information, Klinefelter 's syndrome http://www.patient.co.uk/health/klinefelters-syndrome Klinefelter syndrome-better health channel. In (2012), VGCS-Leaders in genetic health. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Klinefelter_syndrome Klinefelter syndrome information and support in (2013) http://www.klinefeltersyndrome.org/index.htm