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How Did Rosalind Franklin Study DNA?

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How Did Rosalind Franklin Study DNA?
Rosalind Franklin was an English chemist who in 1951, started working on on studying DNA by using a technique called X-ray diffraction. Her expertise was the X-ray diffraction mostly of proteins and lipids in a solution on DNA fibers. Franklin and a student, Raymond Gosling, took pictures of DNA and made the observation that there are two forms of DNA; the “A” form, which is dry and the”B” form, which is wet. One of their pictures of this observations, known as Photograph 51, became famous and was analytical evidence in discovering the structure of DNA. the photograph was finally finished after 100 hours of X-ray exposure from a machine that she had made some changes to herself. Franklin and a colleague, Maurice Wilkins, had a personality conflict …show more content…
Griffith's experiment involved mice and two types of pneumonia – one was virulent and the other non-virulent. He injected the virulent pneumonia into a mouse and the result was the mouse dying. Next he injected the non-virulent pneumonia into a mouse and the result was the mouse surviving. After these tests, to kill the virulent disease; he heated it up and then injected it into a new mouse. This trial was a success, as predicted. Lastly, he injected non-virulent pneumonia and virulent pneumonia that had been heated and killed, into a mouse. This time the mouse died. Griffith speculated that the killed virulent bacteria had passed on a characteristic to the non-virulent one to make it virulent. He believed this characteristic was in the inheritance molecule. This passing on of the inheritance molecule was what he called transformation. Oswald Avery continued with Griffith’s experiment around a decade later to see what the inheritance molecule was. In this experiment he destroyed the lipids, ribonucleic acids, carbohydrates, and proteins of the virulent pneumonia. Transformation still occurred after this. Next he destroyed the deoxyribonucleic acid. Transformation did not occur however. He had found the basis of the

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