Grant Proposa

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Fibrinolytic vs. PCI therapy Grant Proposal
Francesca Tierney
UWF, College of Letters and Sciences, Biology Department, SAHLS Health Science Research Seminar, HSC4050
James Hunt
11/16/2012

Executive Summary

Fibrinolytic therapy has been a significant means of establishing reperfusion in patients whom have had a myocardial infarction or some sort of blood clot. However, limitations to the use of thrombolytic therapy that must be taken in to account are intracranial bleeding, inability to start thrombosis in Myocardial Infarction flow in patients, and high percentage of recurrent ischemia and reocclusion. Primary percutaneous coronary intervention (PCI) has become known as the ideal reperfusion strategy.

The proposed research will be a randomized controlled clinical trial study that will explore the roles of Fibrinolytic therapy vs. PCI in patients whom have received one of the two-reperfusion therapies, and examine the effects of each and symptoms caused. Additionally, therapy effects will be investigated for their potential to positively or negatively impact patient health, and efficiency of the procedure.

Statement of Need

Myocardial infarction also known as a heart attack, takes place when blood flow is interrupted to a part of your heart, allowing a blood clot to obstruct a coronary artery supplying blood to the heart and the heart muscle dies. Each year, the American Heart Association brings together the most up-to-date statistics on heart attacks, and their risk factors. In 2010, the estimate on heart attacks in the U.S. is about $316 billion in order to provide health care, and medicines. A myocardial infarction is indeed one of the most serious illnesses in the world. In the United States alone, 785,000 people undergo their first heart attack and another 470,000 experience a second heart attack every year. With about 1.5 million people suffering from a heart...
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