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Genetics and Unaffected Female Generation

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Genetics and Unaffected Female Generation
Associate Program Material

Genetics Worksheet

Review the images below and answer the follow-up questions.

Questions:

1. According to the pedigree, is cystic fibrosis inherited as a dominant or as a recessive trait? Explain how you made your conclusion using evidence from the pedigree and the principles of genetics. Cystic fibrosis is a recessive trait. If you have one CF gene and one non-CF gene, you will be a carrier but not have CF. I referred back to Mendel mentioning that the trait may not show up in somebody but it can still be passed on to the next generation. He also states that the inheritance of each trait is determined by genes that are passed on unchanged. So as the CF gene is not present, it becomes present depending on the ratio of genes as it passes down.

2. What would a Punnett square that shows how the son in generation IV (marked with an A) inherited cystic fibrosis look like?

C- not a carrier of CF c- carrier
| |c |c |
|C |Cc |Cc |
|c |cc |cc |

Questions:

1. According to the pedigree, is Huntington’s disease inherited as a dominant or as a recessive trait? Explain how you made your conclusion using evidence from the pedigree and the principles of genetics. The gene for Huntington's disease is dominant. Therefore, most people who sufferers have one copy of the expanded gene and one copy of the normal gene.

2. What would a Punnett square that shows how the first daughter in generation II (marked with a B) did not inherit Huntington’s disease look like?
| |B |b |
|b |Bb |bb |
|b |Bb |bb |

3. What is the role of chromosomes in the inheritance of genetic traits, such as cystic fibrosis and Huntington’s disease?

Chromosomes carry the genetic traits.

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