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Food Dyes Research Paper

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Food Dyes Research Paper
Food Dyes
A Rainbow of Risks

Sarah Kobylewski, Ph.D. CandidateMolecular Toxicology Program
University of California, Los Angeles and Michael F. Jacobson, Ph.D.
Executive Director
Center for Science in the Public Interest

Copyright © 2010 by Center for Science in the Public Interest
First Printing June 2010
Printing: 5 4 3 2 1

Summary
Food dyes, synthesized originally from coal tar and now petroleum, have long been controversial. Many dyes have been banned because of their adverse effects on laboratory animals. This report finds that many of the nine currently approved dyes raise health concerns.

Blue 1 was not found to be toxic in key rat and mouse studies, but an unpublished study suggested the possibility that Blue
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Considering the safety questions and its non-essentiality, Red 40 should be excluded from foods unless and until new tests clearly demonstrate its safety.

Yellow 5 was not carcinogenic in rats, but was not adequately tested in mice. It may be contaminated with several cancer-causing chemicals. In addition, Yellow 5 causes sometimes-severe hypersensitivity reactions in a small number of people and might trigger hyperactivity and other behavioral effects in children. Posing some risks, while serving no nutritional or safety purpose, Yellow 5 should not be allowed in foods.

Yellow 6 caused adrenal tumors in animals, though that is disputed by industry and the FDA. It may be contaminated with cancer-causing chemicals and occasionally causes severe hypersensitivity reactions. Yellow 6 adds an unnecessary risk to the food supply. Almost all the toxicological studies on dyes were commissioned, conducted, and analyzed by the chemical industry and academic consultants. Ideally, dyes (and other regulated chemicals) would be tested by independent researchers. Furthermore, virtually all the studies tested individual dyes, whereas many foods and diets contain
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• Red 3 was acknowledged by the FDA to be a carcinogen in 1985 and was banned in cosmetics and externally applied drugs. However Red 3 is still used in ingested drugs and foods. • The three most widely used dyes (Red 40, Yellow 5, Yellow 6) which account for 90% of dyes in the U.S. are contaminated with low levels of chemical carcinogens, as byproducts of the manufacturing process. Although the FDA places limits on the concentrations of these contaminants in the final dye products, they still may pose risks. • Citrus Red 2 added to the diet resulted in bladder tumors. • Red 3 resulted in thyroid tumors and caused DNA damage.
The simplest and most effective way to avoid the potential harmful effects of synthetic dyes is to avoid processed foods. Unrefined plant foods contain health promoting phytochemicals, not empty calories and synthetic additives of questionable safety. When buying the occasional packaged food, check the ingredient list to avoid synthetic

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