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Ethyne Glycol Research Paper

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Ethyne Glycol Research Paper
A chemical that is used every day by almost every person around the world is ethylene glycol. Many people know this chemical by its common name of antifreeze, but it is also used as a solvent and in hydraulic brake fluids. This liquid chemical is clear and colorless with primary threats to the environment through penetrations of soil and groundwater systems. Ethylene glycol can also cause acute and chronic health problems if exposed to. (Ethylene Glycol) There are three main routes of exposure for ethylene glycol: inhalation, ingestions, and skin and eye contact. Ethylene glycol has low volatility, but becomes hazardous to inhale when heated, sprayed, or agitated. The chemical can cause mild irritation to the skin. Ingestion is the fasted …show more content…
Testing is performed for LC50 by calculating the concentration of ethylene glycol over a specific time until a 50% death rate is reached.( OSH Answers Fact Sheets) Goldfish (Carassius auratus) LC50 equals >5,000,000 ug/L concentration for 24 hours. Rainbow trout (Oncorhynchus mykiss) LC50 equals >20000000 ug/L concentration for 96 hours. Atlantic salmon (Salmo salar) LC50 equals >1000000 ug/L concentration for 24 hours. LD50 is determined by given a known amount of ethylene glycol to test animals that cause the death of 50% of the test subjects. (OSH Answers Fact Sheets) A mouse (Mus) LD50 for oral consumption equals 5,500 mg/kg. Rat (Rattus) LD50 for oral consumption equals 4,700 mg/kg. Rabbit (Oryctolagus cuniculus) LD50 for applied to the skin equals 9,530 uL/kg. (Material Safety Data Sheet Ethylene Glycol) There have been several studies done with animal trying to determine if ethylene glycol is a carcinogen, but none of the studies have produced any association between the two. It is determine thought that since ethylene glycol is teratogenic to humans since studies on mice and rats have shown results of skeletal dysplasia, neural tube closure and craniofacial effects. (Medical Management Guidelines for Ethylene Glycol) There have been no links showing that ethylene glycol is a
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