Preview

epigenetics

Better Essays
Open Document
Open Document
1218 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
epigenetics
Genetic research is huge part of modern science. In the past 60 years, starting with James Watson and Francis Crick’s double helix DNA structure, discoveries in the field of genetics have revolutionized the way we look at life (Wright, 2003). As scientists learn more about the blueprints that make up life, more is revealed, to those with a Christian worldview, about how God works and creates within the natural world. One of the fields within genetic research that has been on the forefront of scientific discovery for the past few years is that of epigenetics. The existence of epigenetics has profound implications on relating the biblical worldview to scientific discovery, and as scientists understand more about epigenetics, more biblical parallels are revealed.

To understand implications that come with epigenetics, one must first understand epigenetics. So, what exactly is it? Simply put, epigenetics is the study of changes in gene expression not caused by alterations to the DNA sequence (Berger, Kouzarides, Shiekhattar, & Shilartifard, 2009). Recent studies have shown that the relation between DNA sequence and cell structure is not 1:1, that is to say that what you see in a creature’s DNA does not fully represent what the creature will be like (Berger, Kouzarides, Shiekhattar, & Shilartifard, 2009). Scientists have discovered that there are factors outside DNA structure that influence which parts of a DNA strand will be read and which will not. These factors can be further influenced by experiences within a creature’s lifetime (Berger, Kouzarides, Shiekhattar, & Shilartifard, 2009). This means that what humans do during their lifetime actually has an impact on their genetic code, and consequently, on the genetic code of their offspring. A common method used to explain the epigenetic phenomena is the light switch analogy: we as human beings make decisions and are subject to different events in our lifetime, these events and decisions effect our genetic code by



References: Wright, R. T. (2003) biology through the eyes of faith, Harper Collins San Fransisco 10:194 S. L. Berger, T. Kouzarides, R. Shiekhattar, A. Shilartifard. (2009) An operational defintion of epigenetics. Genes Dev. 23: 781-78.3. Available at: http://genesdev.cshlp.org/content/23/7/781.full.pdf+html C. A. Cooney, A. A. Dave, G. L. Wolff (2002) Maternal Methyl Supplements in Mice Affect Epigenetic Variation and DNA Methylation of Offspring, The American Society for Nutritional Sciences. Available at: http://jn.nutrition.org/content/132/8/2393S.short D. Ziech, R. Franco, A. Pappa, V. Malamou-Mitsi, S. Georgakila, A. G. Georgakilas. (2010) The role of epigenetics in environmental and occupational carcinogenesis. Vol. 188 .340–349. Available at: http://www.sciencedirect.com/science/article/pii/S0009279710003947 F. Johannes, E. Penninsi. (2013) Evolution Heresy? Epigenetics Underlies Heritable Plant Traits. AAAS.org Found at: http://livasperiklis.files.wordpress.com/2013/06/evolution-heresy-epigenetics-underlies-heritable-plant-traits.pdf

You May Also Find These Documents Helpful

  • Better Essays

    Chong Susan DSR 610 Final

    • 963 Words
    • 3 Pages

    islands are normally heavily methylated. However, this can be reversed by treating cells with 5Azacytidine (5’azaC). First studied in 1979 by fellow USC researchers, 5’azaC is an FDAapproved chemotherapeutic agent that is also a DNA methylation inhibitor [4]. By forcing…

    • 963 Words
    • 3 Pages
    Better Essays
  • Better Essays

    Chong Susan DSR 610 Final

    • 963 Words
    • 3 Pages

    islands are normally heavily methylated. However, this can be reversed by treating cells with 5Azacytidine (5’azaC). First studied in 1979 by fellow USC researchers, 5’azaC is an FDAapproved chemotherapeutic agent that is also a DNA methylation inhibitor [4]. By forcing…

    • 963 Words
    • 3 Pages
    Better Essays
  • Powerful Essays

    References: Enger. E., Ross, F. & Bailey, D. (2012). Concepts in Biology 14th Edition. New York, New York: McGraw-Hill. Print.…

    • 1575 Words
    • 7 Pages
    Powerful Essays
  • Good Essays

    Matt is a history teacher. His twin brother Greg is a drug addict. Growing up in the Boston area, both boys did well in high school: they were strong students in the classroom and decent athletes on the field, and they got along with their peers. Like many young people, the brothers drank the occasional beer, smoked cigarettes and experimented with marijuana. Then, in college, they tried cocaine. For Greg, the experience derailed his life. The questions that have risen from this are: what made Greg so susceptible to the grasps of cocaine- to the point that the drug essentially destroyed his life? And how did his identical twin, who shares the exact same genes, escape a similar fate? And how can exposure to a drug set up some individuals for a lifelong addiction, while others can move past their youthful indiscretions and go on to lead productive lives? These questions, although not new, have lead neuroscientist to begin taking a fresh approach to finding the answers. New findings suggest that experience can contribute to mental illness by adding or removing “epigenetic” marks on chromosomes. These tags are particular chemicals that can influence gene activity without changing the information encoded in the gene.…

    • 845 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Epigenetics is a termed coined from epigenome. It is the study of occurrence of changes in the human genome as a result of gene modification expression raising from factors such as lifestyle. The PBS video presents the efforts and advancements made in epigenetics. It is fascinating to realize two people who are identical due to their DNA like twins turn up to be totally different due to alteration of their genes. Great effort has been dedicated in the study of epigenetics in an effort of curbing inherent diseases such as cancer. The breakthrough presented in the video sheds light in the fight against incurable diseases such as cancer as the realization that genes can be altered and modified by what people eat is an interesting breakthrough phenomena.…

    • 1121 Words
    • 5 Pages
    Good Essays
  • Satisfactory Essays

    Methapyrilene, a histamine antagonist belongs to the class of pyridine chemicals, was widely used in many non-prescription drugs until 1979, when it was demonstrated to cause the development of liver tumors in rats. Because of the absence of DNA adducts in the livers of rats treated with methapyrilene, the hepatocarcinogenicity of methapyrilene has been attributed to non-genotoxic mechanisms, mainly to induction of mitochondrial dysfunction and disruption of the cellular epigenome. Indeed, exposure to methapyrilene caused target organ-specific epigenetic alterations that consisted of a reduction in the levels of cytosine DNA methylation and demethylation and deacetylation of histone lysine residues, with the greatest decrease…

    • 164 Words
    • 1 Page
    Satisfactory Essays
  • Good Essays

    The field of epigenetics is “the study of heritable changes in gene activity which are not caused by changes in the DNA sequence” (“Wikipedia”; n.d.). One can adopt a healthy lifestyle to change the impact of the genes inherited by an offspring. Ornish states that changing eating habits, loving more, and getting more exercise can cause a large increase in brain cells. (“ted.com/speakers”; n.d.) These changes could also impact the number of disease provoking genes that one will pass on to an offspring.…

    • 781 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Ghost in Your Genes

    • 703 Words
    • 3 Pages

    Genetic inheritance was thought to have involve the transmission of DNA from one generation to the next affected by occasional mutations in the DNA itself. They found out that the human genome was less complex and had less genes then even less complex organisms such as plants. The human genome, only containing about 30,000 genes, now lead scientists to believe that other factors allow genes to be switched on and off in response to the environment. Professor Pembrey was drawn to two genetic diseases due to families exhibiting unconventional genetic inheritance patterns. The two diseases were Angelman syndrome, which displays clinical symptoms of jerky movements, little or no speech and a very happy personality, and Prader-Willi syndrome, in which patients are found to be very floppy in infancy and develop an insatiable appetite associated with obesity in later life. He found out that these two diseases were caused by the same genetic alteration. There was a small deletion on chromosome 15. The parent from whom the mutation was inherited determined which disease the patient would get. If it was inherited from the mother the child would have Angelman syndrome and if it was inherited from the father the child would have Prader-Willi syndrome. This suggested that the chromosome knew its origin and must had been tagged or imprinted in some way. This was known as genomic imprinting. During sperm and egg production(meiosis), a chemical change results in the same DNA sequence on each chromosome having different functional properties. These events can lead to a particular gene being turned on or off. This is what epigenetics is based of. Professor Reik noticed that when a mouse embryo was placed in a culture dish some of genes would be switched off and wondered whether this could also be true for human embryos during in vitro fertilization or IVF. Using the disease, Beckwith-Wiedeman syndrome, Reik discovered that Beckwith-Wiedeman syndrome occurs…

    • 703 Words
    • 3 Pages
    Good Essays
  • Good Essays

    This is an awesome book. It describes the outlook of biology not only through the eyes of faith, but from a Christian theistic point of view. In Biology through the Eyes of Faith, it explains the difference between a scientist’s perception of nature oppose to a Christian’s perception. Scientists say the world evolved which conflicts with the theistic view, which says the world came about through the creator God.…

    • 2342 Words
    • 10 Pages
    Good Essays
  • Powerful Essays

    Epigenetics

    • 2073 Words
    • 9 Pages

    * 1) A majority of genetically engineered crops in production worldwide today have been engineered with a gene that:…

    • 2073 Words
    • 9 Pages
    Powerful Essays
  • Good Essays

    TEDX. (2014). Prenatal Origins of Endocrine Disruption. Retrieved November 24, 2014, from The Edocrine Disruption Exchange: http://endocrinedisruption.org/prenatal-origins-of-endocrine-disruption/prenatal-origins-of-cancer/overview…

    • 747 Words
    • 2 Pages
    Good Essays
  • Good Essays

    Autism

    • 732 Words
    • 3 Pages

    References: 1. Zhang, Yu-Wen, Kyle A. Furge, Ben Staal, Karl J. Dykema, and George F. Vande Woude. "PLOS ONE: Cancer-Type Regulation of MIG-6 Expression by Inhibitors of Methylation and Histone Deacetylation." PLOS ONE: accelerating the publication of peer-reviewed science. N.p., n.d. Web. 6 Oct. 2013. .…

    • 732 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Brain development is an elaborate process, including neuron proliferation, differentiation, migration, communication, and apoptosis. Hereditary deficits and negative environmental exposures can lead to irregular neurological development. The characteristics of neurodevelopmental disorders firmly coincide with the qualities of dysfunctional epigenetic adjustment at the chromatin level, exclusively or in collaboration.…

    • 1033 Words
    • 5 Pages
    Powerful Essays
  • Powerful Essays

    Those that experience post-traumatic stress disorder (PTSD) know that it’s a horrible experience, one that they wouldn’t want to pass on. For those who experienced PTSD provoking trauma it’s a sad reality that their PTSD will be passed on to their children who didn’t experience the traumatic event, creating a cycle. PTSD, among other things, has the ability to be passed down because of epigenetics, the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. Epigenetics is a widely debated topic because it states that children’s genes are negatively changed because of their parents’ trauma. Some critics argue that people with anxiety and health complaints are more aware of their…

    • 1619 Words
    • 7 Pages
    Powerful Essays
  • Powerful Essays

    Rollo C. 1994. Phenotypes : their epigenetics, ecology, and evolution [Internet]. 1st Edition. New York(NY):Chapman & Hall; [cited 2014 Jul 7] Available from: https://library.usc.edu/uhtbin/cgisirsi/x/0/0/5?searchdata1=580728%7BCKEY%7D…

    • 3082 Words
    • 10 Pages
    Powerful Essays

Related Topics