Dosage Forms and Routes of Administration

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  • Topic: Pharmacology, Route of administration, Dosage form
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Ashley Hall

Dosage Forms and Routes of Administration

A dosage form is the physical form of a dose of a chemical compound used as a drug or a medication intended for administration or consumption. Some common dosage forms include the pill, tablet, capsule, drink or syrup, aerosol or inhaler, liquid injection, and pure powder. The route of administration for drug delivery is dependent on the dosage form of the substance. Various dosage forms my exist for a particular drug, since different medical conditions need different routes of administration. A specific dosage form may be a requirement for certain kinds of drugs because of issues with various factors like chemical stability or pharmacokinetics.

The route of administration is a path in which a drug or other substance enters the body. The pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, of a drug are critically influenced by the route of administration. The United States Food and Drug Administration recognizes 111 distinct routes of administration. The development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. The most common routes of administration are oral, sublingual and buccal, rectal, parenteral routes, intraveneous , intramuscular, subcutaneous, intradermal, ophthalmic, intranasasal, inhalation, dermal, and vaginal.

Examples of drugs for different routes of administration:

❖ Oral – Lipitor
❖ Sublingual & Buccal – Nitrostat
❖ Rectal – Eucalyptol Suppositories
❖ Parenteral – Calcium Chloride
❖ Intravenous – Morphine
❖ Intramuscular – Progesterone

❖ Subcutaneous – Heparin

❖ Intradermal – Lidocaine

❖ Opthalmic – Quixin

❖ Intanasal – Flumist

❖ Inhalation – Proventil

❖ Dermal – Nix

❖ Vaginally – Azole
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