determination of vitamin c content of tablet
DETERMINATION OF VITAMIN C CONTENT IN COMMERCIAL (CENOVIS) TABLET
ABSTRACT
In this experiment, the vitamin C content of a commercial tablet is determined and compared with the manufacturers’ specification. Vitamin C is water-soluble and is an enantiomer of ascorbic acid. (Commercial vitamin C is often a mixture of ascorbic acid and other ascorbates.) Ascorbic acid, C6H8O6, is a reducing agent that reacts rapidly with iodine (I2). As the iodine is added during the titration, the ascorbic acid is oxidized to dehydroascorbic acid, while the iodine is reduced to iodide ions as shown in the following equation: (studymode.js, 2010).
Ascorbic acid + I2 (aq) -----------> 2I- (aq) + dehydroascorbic acid
Due to this reaction, the iodine formed is immediately reduced to iodide as long as there is any ascorbic acid present. The amount of ascorbic acid is determined by the stoichiometry of the equations and the difference between the total amount of iodine present and the amount that reacts with the thiosulphate. This method is suitable for use with vitamin C tablets, fresh or packaged fruit juices and solid fruits and vegetables.
INTRODUCTION
Vitamins are a group of small molecular compounds that are essential nutrients in many multi-cellular organisms, and humans in particular. L-Ascorbic acid was first isolated as a pure substance by Albert Azent-Gyorgi and Charles Kingin 1928 (Pauling, 1970), an anti-oxidant and free radical scavenger, is found ubiquitously in fruit and vegetables such as citrus fruits (oranges, lemons, limes, tangerines etc.), melons, tomatoes, peppers, broccoli, green leafy vegetables such as spinach, potatoes and turnips, its quantitative determination is especially important in the production of wine, beer, milk, soft drinks and fruit juices, where it can be a quality indicator (Gerrior & Zizza, 1994)] .Given the essential role played in the human diet and necessary to growth and repair of tissues in all parts of human body .It is
ABSTRACT
In this experiment, the vitamin C content of a commercial tablet is determined and compared with the manufacturers’ specification. Vitamin C is water-soluble and is an enantiomer of ascorbic acid. (Commercial vitamin C is often a mixture of ascorbic acid and other ascorbates.) Ascorbic acid, C6H8O6, is a reducing agent that reacts rapidly with iodine (I2). As the iodine is added during the titration, the ascorbic acid is oxidized to dehydroascorbic acid, while the iodine is reduced to iodide ions as shown in the following equation: (studymode.js, 2010).
Ascorbic acid + I2 (aq) -----------> 2I- (aq) + dehydroascorbic acid
Due to this reaction, the iodine formed is immediately reduced to iodide as long as there is any ascorbic acid present. The amount of ascorbic acid is determined by the stoichiometry of the equations and the difference between the total amount of iodine present and the amount that reacts with the thiosulphate. This method is suitable for use with vitamin C tablets, fresh or packaged fruit juices and solid fruits and vegetables.
INTRODUCTION
Vitamins are a group of small molecular compounds that are essential nutrients in many multi-cellular organisms, and humans in particular. L-Ascorbic acid was first isolated as a pure substance by Albert Azent-Gyorgi and Charles Kingin 1928 (Pauling, 1970), an anti-oxidant and free radical scavenger, is found ubiquitously in fruit and vegetables such as citrus fruits (oranges, lemons, limes, tangerines etc.), melons, tomatoes, peppers, broccoli, green leafy vegetables such as spinach, potatoes and turnips, its quantitative determination is especially important in the production of wine, beer, milk, soft drinks and fruit juices, where it can be a quality indicator (Gerrior & Zizza, 1994)] .Given the essential role played in the human diet and necessary to growth and repair of tissues in all parts of human body .It is
Cited: Gerrior, S., & Zizza, C. (1994). Nutrient content of the U.S food supply, 1909-1990. Washington D.C: U.S department of Agriculture. Mcevoy, G. (1993). Drug information the american hospital formulary service. American society of health-system pharmacist. Pauling, l. (1970). vitamin c and the common cold. studymode.js. (2010). commercial vitamin c tablet analysis. Retrieved from studymode: http://www.studymode.com/essays/Commercial-Vitamin-c-Tablets-Analysis-470526.html