It is a neurologic disorder and is occur as a result of disruption in nerve cell activity in the brain causing seizure or unusual behavior, sensation and sometime loss on consciousness.
Type of seizure:
1. Focal seizures: there is disruption in one area of brain.
A. Simple partial seizure.
B. Complex partial seizure.
2. Generalized seizure: there is disruption in all area of brain.
A. Absence seizure.
B. Tonic seizure.
C. Atonic seizure.
D. Clonic seizure.
E. Myoclonic seizure.
F. Toni-Clonic seizure.
Symptoms:
It’s varies depend on type of seizure. o Temporary confusion o Staring spell o Uncontrollable jerking movement of the arms and legs o Loss of consciousness o Psychic symptoms
Causes:
o Genetic …show more content…
o Sulfonamides: Zonisamide o Benzodiazepine: Lorazepam, Diazepam, Clonazepam. o Barbiturates: phenobarbital, primidone. o Sulfamate-substitute monosaccharides: Topiramate.
Consequences of drug interaction with anti-seizures drugs:
- Carbamazepine and Norco (acetaminophen/ hydrocodone)… carbamazepine will decrease hydrocodone blood level and this will decrease effectiveness of hydrocodone, also it may cause unpleasant withdrawal symptoms such as runny nose, water eyes, sneezing, excessive sweating, fever, chill, flushing, restlessness, irritability, anxiety, depression, pupil dilation. In some situation, the doctor may prescribe the two drugs but with adjustment dose, so if the patient stops the carbamazepine without the dose readjustment it will lead to hydrocodone overdose due to increase the blood level of hydrocodone.
Carbamazepine and acetaminophen together will lead to serious side effect of acetaminophen that affect the liver.
- Diazepam and propoxyphene: It will increase serious side effect of propoxyphene for example, dizziness, drowsiness, confusion, difficulty concentrating, impairment in thinking, judgment, motor coordinator and in some cases