In Power Failure, Megan Scudellari talks about mitochondrial dysfunction and how it can influence complex diseases. She introduces Douglass Wallace and talks about how he came up with this idea that maybe the mitochondria is linked to certain diseases such as Alzheimer’s and cancers. He was the first person ever to discover that mutations in mtDNA cause disease and from that point on his research began to expand. At first many scientists turned a blind eye to this theory, assuming that it wasn’t true and that complex diseases were nothing but complex, but as the years went on and more and more research had been done many scientists began to actually consider this theory a possibility. As time goes on Wallace’s idea becomes more and more true. They now know that mutation is connected to impaired mitochondrial function and now Wallace has opened The Center for Mitochondrial and Epigenomic Medicine to perform more research on the mitochondria of cells.
My opinion on this article was that it was not very interesting. It was mostly just reading off information instead of there actually being some kind of story to it. I do think though that this article was very informative. If they continue with this research and find out more about how the mutations in mtDNA “create” complex diseases I strongly think there may be a possibility that they could find cures for many of them such as cancer. Even though there has been billions of dollars’ worth of research on a cure for cancer maybe they have been looking in the wrong places and excluding the possibility of the mitochondria. Just because something seems crazy doesn’t mean it is not possible. I think that more scientists should look into Wallace’s theory more, if it could possibly mean a cure why not?
Some new terms I found in this article were biomarkers and mtDNA. A biomarker is a substance used as an indicator of a biological state. It can be introduced into an organism to...