The research was to identify if Lithium was an effective monotherapy treatment for conduct disorder. Lithium or in combination with atypical antipsychotics was explored to identify the negative and positive responses to the treatments. Children and adolescents were examined to determine the effects and tolerability of these treatments. | The Independent Variables for this study were the Lithium monotherapy, Psychostimulants, atypical antipsychotics, and SSRI’sThe Dependent Variables were the children/adolescents’ levels of aggression, as well as behavior in general, and their global assessment of functioning. In terms of predictors the study emphasizes that these are highly debated and can vary greatly. However the study claims that predatory and profitable aggression make patients more likely to be resistant to medication. | Findings Lithium monotherapy treatment improved significantly with exception of self-aggression (p.89). Patients who took lithium along with atypical antipsychotic therapy improved significantly (p/= .80. Between the two treatments, baseline clinical severity and functional impairment assesments indicate no statistical difference. 1/3 of participants had adverse effect that includes vomiting, nausea, stomach complaints, urinary frequency, tremors, thyroid dysfunction and possible weight gain.
The research was to identify if Lithium was an effective monotherapy treatment for conduct disorder. Lithium or in combination with atypical antipsychotics was explored to identify the negative and positive responses to the treatments. Children and adolescents were examined to determine the effects and tolerability of these treatments. | The Independent Variables for this study were the Lithium monotherapy, Psychostimulants, atypical antipsychotics, and SSRI’sThe Dependent Variables were the children/adolescents’ levels of aggression, as well as behavior in general, and their global assessment of functioning. In terms of predictors the study emphasizes that these are highly debated and can vary greatly. However the study claims that predatory and profitable aggression make patients more likely to be resistant to medication. | Findings Lithium monotherapy treatment improved significantly with exception of self-aggression (p.89). Patients who took lithium along with atypical antipsychotic therapy improved significantly (p/= .80. Between the two treatments, baseline clinical severity and functional impairment assesments indicate no statistical difference. 1/3 of participants had adverse effect that includes vomiting, nausea, stomach complaints, urinary frequency, tremors, thyroid dysfunction and possible weight gain.