Alzheimer's disease, a neurodegenerative brain disease, is the most common cause of dementia. It currently afflicts about 4 million Americans and is the fourth leading cause of death in the United States. Alzheimer’s disease is the leading cause of mental impairment in elderly people and accounts for a large percentage of admissions to assisted long-term care facilities. Psychotic symptoms, such as delusions and hallucinations, have been reported in a large proportion of patients with this disease. In fact, it is the presence of these psychotic symptoms can lead to early institutionalization.
Learning about Alzheimer’s disease and realizing that it is much more that just a loss of memory can benefit the families of those with the disorder as well as society. The purpose of this paper is to look at the disorder, as well as to discuss the history, symptoms, diagnosis and hopes of a cure for Alzheimer’s disease.
Around the turn of the century, two kinds of dementia were defined by Emil Kraepin: senile and presenile. The presenile form was described more in detail by Alois Alzheimer as a progressive deterioration of memory and orientation. As a neuropathologist, Alzheimer studied the case a 51 year-old woman. When she died, Alzheimer performed an autopsy and found that she had deterioration of the brain, protein deposits and abnormal filaments in nerve cells in her brain -- three common pathological features of those who have Alzheimer’s Disease.
Today, as research on Alzheimer's disease progresses, scientists are describing other abnormal anatomical and chemical changes associated with the disease. These include nerve cell degeneration in the brain's nucleus and reduced levels of the neurotransmitter acetylcholine in the brains of Alzheimer's disease victims. However, from a practical standpoint, conducting an autopsy of an individual to make a definitive diagnosis is rather ineffective.
The progression of Alzheimer’s disease is...
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