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Wound healing activity of TawaTawa

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Wound healing activity of TawaTawa
177
Global Journal of Medicinal Plant Research, 1(2): 177-183, 2013
ISSN 2074-0883

Assessment of the safety of tawa-tawa (Euphorbia hirta L.) decoction as alternative folkloric medicine
1

Sharon Rose M. Tabugo, 1Rolliebert B. Rampola, 2Edgar Vasallo Jr., 1Ma. Reina Suzette B.
Madamba

1

Department of Biological Sciences, College of Science and Mathematics, MSU-Iligan Institute of Technology,
Iligan City;
2
Capitol University, Cagayan de Oro City
ABSTRACT
Euphorbia hirta L., plant is a pantropic weed, widely distributed in the Philippines. Folkloric use of tawatawa (E. hirta L.), as alternative treatment and prevention for various ailments has been promoted and patronized due to the increasing trend in the quest for inexpensive alternative medicines compared to commercial drugs. Nowadays, the traditional decoction preparation has been widely used however, the safety of its oral use against normal microflora, is still ambiguous despite traditional practice hence, this study. The disc diffusion method was used to determine the antibacterial activity against gram positive and gram negative bacteria (standard strains and clinical isolates). Antibacterial activity was tested on E. coli, S. aureus, B. subtilis and P. aeruginosa. Results show that there was no formation of any zone of inhibition as observed after 24 hrs.
Thus, this justifies the traditional use of the plant as decoction treatment for various ailments. Various concentrations of crude extracts diluted in distilled water were also tested for comparison purposes but it yielded the same results as the decoction procedure. Since, the results were negative for any antibacterial potential, the use of tawa-tawa decoction for oral intake should be highly recommended in the treatment of various conditions without the risk of altering the normal flora of microorganisms in the gastrointestinal tract. Hence, it is safe to use. Key words: Euphorbia hirta L., tawa-tawa, decoction



References: Bate-Smith and Swain, 1962. Flavonoid compounds. In Florkin M., mason H.S. Comparative biochemistry. III. Burkill, H.M., 1985. The useful plant of west tropical Africa. Royal Botanic Gardens, Kew 2nd edn. Elvin-Lewis, M.P.F., W.H. Lewis, 1977. Medical botany: plants affecting man’s health. New York : Wiley. Frohne, D., 1999. Plant intoxicants-is there a risk in herbal preparation? Z. Phytoterapie, 20: 201-202, 205-208. Kerharo, J. and J.G. Adam, 1974. La Pharmacopie Senegalese traditionelle. Plants medicinales etoxique, Vigot press, Paris. Kokwaro, J.O., 1993. Medicinal Plants in the East Africa. 2nd eddn. East African Literature Bureau, Nairobi, Kenya. Kumar, S., Rashnmi and D. Kumar, 2010. Evaluation of antibiotic activity of Euphorbia hirta Linn. In streptozotocin induced diabetic mice Nelofar, A., T. Suhail, S. Ahmad, N. Afza and S.T. Khan, 2006. Evaluation of Antibacterial Activity of a Locally Available Medicinal Plant Euphorbia hirta Ogbulie, J.N., C.C. Ogueke, I.C. Okoli and B.N. Anyanwu, 2007. Antibacterial activities and toxicological potentials of crude ethanolic extracts of Euphorbia hirta Perry, L.M. and J. Metzger, 1980. Medicinal Plants of East and South East Asia. MIT Press Cambridge, London. Ryan, K.J. and C.G. Ray, 2004. Sherris Medical Microbiology 4th ed. McGraw Hill. ISBN 0-8385-8529-9. Soforowa, E.A., 1982. Medicinal plants and traditional medicine in Africa. John Wiley and Sons, Chichester., pp: 198. Todar, K., 2011. The Normal Bacterial Flora in Humans. Todar’s Online Textbook of Bacteriology. Watt, J.M. and B.B. Wijka, 1962. The Medicinal and Poisonous Plants of Southern Eastern Africa 2nd edition. Wong-Ting-Fook, WTH., 1980. The medicinal plants of Mauritius. ENDA publication No. 10., Dakar.

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